Study of the antidiabetic mechanism of berberine compound on FOXO1 transcription factor through molecular docking and molecular dynamics simulations

• Main Authors: Maksum, Iman Permana, Rustaman, Rustaman, Deawati, Yusi, Rukayadi, Yaya, Utami, Ayudiah Rizki, Nafisa, Zahra Khira
• Format: Article
• Published: Springer Science and Business Media Deutschland GmbH 2024
• Online Access: http://psasir.upm.edu.my/id/eprint/113615/; https://link.springer.com/article/10.1007/s00894-024-06060-6?error=cookies_not_supported&code=b6e6fa34-81d9-4715-b19d-62a2ffbf64fc

Context: Diabetes mellitus (DM) is a metabolic disorder disease that causes hyperglycemia conditions and associated with various chronic complications leading to mortality. Due to high toxicity of conventional diabetic drugs, the exploration of natural compounds as alternative diabetes treatments ha...