Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is an extremely difficult disease to manage and one of the ten most common cancers in Malaysia. However, the molecular mechanisms that contribute to tumour progression in hepatocarcinogenesis remain unknown. In recent years, the evidence that the Wnt signaling pathw...

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Main Author: Ban, Kechen
Format: Thesis
Language:English
English
Published: 2002
Online Access:http://psasir.upm.edu.my/id/eprint/11271/1/FPSK_P_2002_1.pdf
http://psasir.upm.edu.my/id/eprint/11271/
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spelling my.upm.eprints.112712024-06-13T07:11:31Z http://psasir.upm.edu.my/id/eprint/11271/ Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma Ban, Kechen Hepatocellular carcinoma (HCC) is an extremely difficult disease to manage and one of the ten most common cancers in Malaysia. However, the molecular mechanisms that contribute to tumour progression in hepatocarcinogenesis remain unknown. In recent years, the evidence that the Wnt signaling pathway may play a crucial role in the hepatocarcinogenesis represents a major breakthrough. Despite efforts made in this area of research, the relationship between the related genes of Wnt signaling pathway is still far from comprehensive. By employing immunohistochemistry and DNA sequencing, some related proteins and genes of the Wnt signaling pathway were investigated in 23 paired HCC and adjacent liver specimens from a tertiary referral centre in Malaysia. 2002-10 Thesis NonPeerReviewed text en http://psasir.upm.edu.my/id/eprint/11271/1/FPSK_P_2002_1.pdf Ban, Kechen (2002) Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma. Doctoral thesis, Universiti Putra Malaysia. English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
English
description Hepatocellular carcinoma (HCC) is an extremely difficult disease to manage and one of the ten most common cancers in Malaysia. However, the molecular mechanisms that contribute to tumour progression in hepatocarcinogenesis remain unknown. In recent years, the evidence that the Wnt signaling pathway may play a crucial role in the hepatocarcinogenesis represents a major breakthrough. Despite efforts made in this area of research, the relationship between the related genes of Wnt signaling pathway is still far from comprehensive. By employing immunohistochemistry and DNA sequencing, some related proteins and genes of the Wnt signaling pathway were investigated in 23 paired HCC and adjacent liver specimens from a tertiary referral centre in Malaysia.
format Thesis
author Ban, Kechen
spellingShingle Ban, Kechen
Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma
author_facet Ban, Kechen
author_sort Ban, Kechen
title Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma
title_short Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma
title_full Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma
title_fullStr Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma
title_full_unstemmed Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma
title_sort wnt signaling pathway related genes in hepatocellular carcinoma
publishDate 2002
url http://psasir.upm.edu.my/id/eprint/11271/1/FPSK_P_2002_1.pdf
http://psasir.upm.edu.my/id/eprint/11271/
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