Maternal COVID-19 vaccine acceptance among Malaysian pregnant women: A multicenter cross-sectional study

Introduction: The coronavirus disease 2019 (COVID-19) caused a global pandemic that resulted in devastating health, economic and social disruption. Pregnant mothers are susceptible to COVID-19 complications due to physiological and immunity changes in pregnancy. We aimed to assess the maternal vacci...

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Main Authors: Kalok, Aida, Razak Dali, Wira, Sharip, Shalisah, Abdullah, Bahiyah, Kamarudin, Maherah, Dasrilsyah, Rima Anggrena, Abdul Rahman, Rahana, Kamisan Atan, Ixora
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Published: Frontiers Media 2023
Online Access:http://psasir.upm.edu.my/id/eprint/110075/
https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2023.1092724/full
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spelling my.upm.eprints.1100752024-09-05T07:35:53Z http://psasir.upm.edu.my/id/eprint/110075/ Maternal COVID-19 vaccine acceptance among Malaysian pregnant women: A multicenter cross-sectional study Kalok, Aida Razak Dali, Wira Sharip, Shalisah Abdullah, Bahiyah Kamarudin, Maherah Dasrilsyah, Rima Anggrena Abdul Rahman, Rahana Kamisan Atan, Ixora Introduction: The coronavirus disease 2019 (COVID-19) caused a global pandemic that resulted in devastating health, economic and social disruption. Pregnant mothers are susceptible to COVID-19 complications due to physiological and immunity changes in pregnancy. We aimed to assess the maternal vaccine acceptance of the COVID-19 vaccine. Methods: A multi-center study across four teaching hospitals in the Klang Valley, Malaysia was conducted between September 2021 and May 2022. A survey was conducted using a self-administered electronic questionnaire. The survey instruments included; (1) maternal perception and attitude toward COVID-19 vaccination, (2) COVID-19 pregnancy-related anxiety, and 3) generalized anxiety disorder. Results: The response rate was 96.6%, with a final number for analysis of 1,272. The majority of our women were Malays (89.5%), with a mean age (standard deviation, SD) of 32.2 (4.6). The maternal vaccine acceptance in our study was 77.1%. Household income (p < 0.001), employment status (p = 0.011), and health sector worker (p = 0.001) were independent predictors of maternal willingness to be vaccinated. COVID-19 infection to self or among social contact and greater COVID-19 pregnancy-related anxiety were associated with increased odds of accepting the SARS-CoV-2 vaccine. Women who rely on the internet and social media as a source of vaccine information were more likely to be receptive to vaccination (adjusted odd ratio, AOR 1.63; 95% CI 1.14–2.33). Strong correlations were observed between maternal vaccine acceptance and the positive perception of (1) vaccine information (p < 0.001), (2) protective effects of vaccine (p < 0.001), and (3) getting vaccinated as a societal responsibility (p < 0.001). Discussion: The high maternal vaccine acceptance rate among urban pregnant women in Malaysia is most likely related to their high socio-economic status. Responsible use of the internet and social media, alongside appropriate counseling by health professionals, is essential in reducing vaccine hesitancy among pregnant women. Frontiers Media 2023 Article PeerReviewed Kalok, Aida and Razak Dali, Wira and Sharip, Shalisah and Abdullah, Bahiyah and Kamarudin, Maherah and Dasrilsyah, Rima Anggrena and Abdul Rahman, Rahana and Kamisan Atan, Ixora (2023) Maternal COVID-19 vaccine acceptance among Malaysian pregnant women: A multicenter cross-sectional study. Frontiers in Public Health, 11. art. no. 1092724. pp. 1-11. ISSN 2296-2565 https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2023.1092724/full 10.3389/fpubh.2023.1092724
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
description Introduction: The coronavirus disease 2019 (COVID-19) caused a global pandemic that resulted in devastating health, economic and social disruption. Pregnant mothers are susceptible to COVID-19 complications due to physiological and immunity changes in pregnancy. We aimed to assess the maternal vaccine acceptance of the COVID-19 vaccine. Methods: A multi-center study across four teaching hospitals in the Klang Valley, Malaysia was conducted between September 2021 and May 2022. A survey was conducted using a self-administered electronic questionnaire. The survey instruments included; (1) maternal perception and attitude toward COVID-19 vaccination, (2) COVID-19 pregnancy-related anxiety, and 3) generalized anxiety disorder. Results: The response rate was 96.6%, with a final number for analysis of 1,272. The majority of our women were Malays (89.5%), with a mean age (standard deviation, SD) of 32.2 (4.6). The maternal vaccine acceptance in our study was 77.1%. Household income (p < 0.001), employment status (p = 0.011), and health sector worker (p = 0.001) were independent predictors of maternal willingness to be vaccinated. COVID-19 infection to self or among social contact and greater COVID-19 pregnancy-related anxiety were associated with increased odds of accepting the SARS-CoV-2 vaccine. Women who rely on the internet and social media as a source of vaccine information were more likely to be receptive to vaccination (adjusted odd ratio, AOR 1.63; 95% CI 1.14–2.33). Strong correlations were observed between maternal vaccine acceptance and the positive perception of (1) vaccine information (p < 0.001), (2) protective effects of vaccine (p < 0.001), and (3) getting vaccinated as a societal responsibility (p < 0.001). Discussion: The high maternal vaccine acceptance rate among urban pregnant women in Malaysia is most likely related to their high socio-economic status. Responsible use of the internet and social media, alongside appropriate counseling by health professionals, is essential in reducing vaccine hesitancy among pregnant women.
format Article
author Kalok, Aida
Razak Dali, Wira
Sharip, Shalisah
Abdullah, Bahiyah
Kamarudin, Maherah
Dasrilsyah, Rima Anggrena
Abdul Rahman, Rahana
Kamisan Atan, Ixora
spellingShingle Kalok, Aida
Razak Dali, Wira
Sharip, Shalisah
Abdullah, Bahiyah
Kamarudin, Maherah
Dasrilsyah, Rima Anggrena
Abdul Rahman, Rahana
Kamisan Atan, Ixora
Maternal COVID-19 vaccine acceptance among Malaysian pregnant women: A multicenter cross-sectional study
author_facet Kalok, Aida
Razak Dali, Wira
Sharip, Shalisah
Abdullah, Bahiyah
Kamarudin, Maherah
Dasrilsyah, Rima Anggrena
Abdul Rahman, Rahana
Kamisan Atan, Ixora
author_sort Kalok, Aida
title Maternal COVID-19 vaccine acceptance among Malaysian pregnant women: A multicenter cross-sectional study
title_short Maternal COVID-19 vaccine acceptance among Malaysian pregnant women: A multicenter cross-sectional study
title_full Maternal COVID-19 vaccine acceptance among Malaysian pregnant women: A multicenter cross-sectional study
title_fullStr Maternal COVID-19 vaccine acceptance among Malaysian pregnant women: A multicenter cross-sectional study
title_full_unstemmed Maternal COVID-19 vaccine acceptance among Malaysian pregnant women: A multicenter cross-sectional study
title_sort maternal covid-19 vaccine acceptance among malaysian pregnant women: a multicenter cross-sectional study
publisher Frontiers Media
publishDate 2023
url http://psasir.upm.edu.my/id/eprint/110075/
https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2023.1092724/full
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