In vivo toxicity assessment of the probiotic Bacillus amyloliquefaciens HTI-19 isolated from stingless bee (Heterotrigona itama) honey

• Main Authors: Zulkhairi Amin, Fatin Aina, Shafiq Cheng, Mohamad Zulhafiz, Sabri, Suriana, Ismail, Norsharina, Chan, Kim Wei, Mohd Esa, Norhaizan, Mohd Lila, Mohd Azmi, Nur-Fazila, Saulol Hamid, Khalifa, Shaden A. M., El-Seedi, Hesham R., Zawawi, Norhasnida
• Format: Article
• Published: Multidisciplinary Digital Publishing Institute 2023
• Online Access: http://psasir.upm.edu.my/id/eprint/109403/; https://www.mdpi.com/2072-6643/15/10/2390#:~:text=This%20study%20assessed%20the%20toxicity,administered%20to%20the%20treated%20rats.

This study evaluated the acute and sub-acute toxicity of B. amyloliquefaciens HTI-19 (isolated from stingless bee honey) in female Sprague Dawley rats. In an acute toxicity study, the rats received a low dosage (1 × 109 CFU·mL−1 ), medium dosage (3 × 109 CFU·mL−1 ), or high dosage (1 × 1010 CFU·mL−1...