Multiclonal human origin and global expansion of an endemic bacterial pathogen of livestock

• Main Authors: Yebra, Gonzalo, Harling-Lee, Joshua D., Lycett, Samantha, Aarestrup, Frank M., Larsen, Gunhild, Cavaco, Lina M., Seo, Keun Seok, Abraham, Sam, Norris, Jacqueline M., Schmidt, Tracy, Ehlers, Marthie M., Sordelli, Daniel O., Buzzola, Fernanda R., Gebreyes, Wondwossen A., Gonçalves, Juliano L., dos Santos, Marcos V., Zakaria, Zunita, Rall, Vera L. M., Keane, Orla M., Niedziela, Dagmara A.
• Format: Article
• Language: English
• Published: National Academy of Sciences 2022
• Online Access: http://psasir.upm.edu.my/id/eprint/108646/1/108646.pdf; http://psasir.upm.edu.my/id/eprint/108646/; https://www.pnas.org/doi/10.1073/pnas.2211217119

Most new pathogens of humans and animals arise via switching events from distinct host species. However, our understanding of the evolutionary and ecological drivers of successful host adaptation, expansion, and dissemination are limited. Staphylococcus aureus is a major bacterial pathogen of humans...