Discogenic low back pain: anatomy, pathophysiology and treatments of intervertebral disc degeneration

• Main Authors: Mohd Isa, Isma Liza, Teoh, Seong Lin, Mohd Nor, Nurul Huda, Mokhtar, Sabarul Afian
• Format: Article
• Language: English
• Published: Multidisciplinary Digital Publishing Institute 2022
• Online Access: http://psasir.upm.edu.my/id/eprint/107354/1/107354.pdf; http://psasir.upm.edu.my/id/eprint/107354/; https://www.mdpi.com/1422-0067/24/1/208

Intervertebral disc (IVD) degeneration is a major contributing factor for discogenic low back pain (LBP), causing a significant global disability. The IVD consists of an inner core proteoglycan-rich nucleus pulposus (NP) and outer lamellae collagen-rich annulus fibrosus (AF) and is confined by a car...