Clinacanthus nutans aqueous extract exerts anti-allergic activity in preclinical anaphylactic models via alternative IgG pathway

• Main Authors: Kow, Audrey Siew Foong, Khoo, Leng Wei, Tan, Ji Wei, Abas, Faridah, Lee, Ming-Tatt, Ahmad Israf, Daud, Shaari, Khozirah, Tham, Chau Ling
• Format: Article
• Language: English
• Published: Elsevier Ireland 2023
• Online Access: http://psasir.upm.edu.my/id/eprint/107035/1/Clinacanthus%20nutans%20aqueous%20extract%20exerts%20anti-allergic%20activity%20in%20preclinical%20anaphylactic%20models%20via%20alternative%20IgG%20pathway.pdf; http://psasir.upm.edu.my/id/eprint/107035/; https://linkinghub.elsevier.com/retrieve/pii/S037887412201042X

Ethnopharmacological relevance Allergy is mediated by the crosslinking of immunoglobulins (Ig) -E or -G to their respective receptors, which degranulates mast cells, macrophages, basophils, or neutrophils, releasing allergy-causing mediators. The removal of these mediators such as histamine, platel...