Acquired radioresistance in EMT6 mouse mammary carcinoma cell line is mediated by CTLA-4 and PD-1 throughJAK/STAT/PI3K pathway

• Main Authors: Ronny Sham, Nur Fatihah, Abdul Hamid Hasani, Narimah, Hasan, Nurhaslina, Abdul Karim, Muhammad Khalis, Syed Ahmad Fuad, Syed Baharom, Hasbullah, Harissa Husainy, Ibahim, Mohammad Johari
• Format: Article
• Published: Nature Publishing Group 2023
• Online Access: http://psasir.upm.edu.my/id/eprint/106413/; https://www.nature.com/articles/s41598-023-29925-x?error=cookies_not_supported&code=698afead-b812-4015-b8da-3e41401724f1

Cancer recurrence is often associated with the acquisition of radioresistance by cancer tissues due to failure in radiotherapy. The underlying mechanism leading to the development of acquired radioresistance in the EMT6 mouse mammary carcinoma cell line and the potential pathway involved was investi...