Cytotoxicity of bismuth(iii) dithiocarbamate derivatives by promoting a mitochondrial-dependent apoptotic pathway and suppressing MCF-7 breast adenocarcinoma cell invasion

• Main Authors: Chan, Pit Foong, Ang, Kok Pian, Abd Hamid, Roslida
• Format: Article
• Published: Springer 2024
• Online Access: http://psasir.upm.edu.my/id/eprint/106261/; https://link.springer.com/article/10.1007/s00775-023-02041-x?error=cookies_not_supported&code=db0203e6-07e0-4941-8119-0c266b69b7e5

We previously reported that the bismuth(III) dithiocarbamate derivative, bismuth diethyldithiocarbamate (1) exhibited greater cytotoxicity while inducing apoptosis via the intrinsic pathway in MCF-7 cells. We further evaluated the other bismuth(III) dithiocarbamate derivatives, BiS2CNR3, with R = (C...