Nanocomposites of iron oxide, sodium alginate, and eugenol induce apoptosis via PI3K/Akt/mTOR signaling in Hep3 cells and in vivo hepatotoxicity in the zebrafish model

• Main Authors: Elderdery, Abozer Y., Alzerwi, Nasser A.N., Alzahrani, Badr, Alsrhani, Abdullah, Alsultan, Afnan, Rayzah, Musaed, Idrees, Bandar, Rayzah, Fares, Baksh, Yaser, Alzahrani, Ahmed M., Alabdulsalam, Abdulrahim A., Mohamedain, A., Subbiah, Suresh Kumar, Mok, Pooi Ling
• Format: Article
• Published: Elsevier B.V. 2024
• Online Access: http://psasir.upm.edu.my/id/eprint/105814/; https://www.sciencedirect.com/science/article/pii/S0141813023043878

Hepatic cancer is among the most recurrently detected malignancies worldwide and one of the main contributors to cancer-associated mortality. With few available therapeutic choices, there is an instant necessity to explore suitable options. In this aspect, Nanotechnology has been employed to explore...