Using a testis regeneration model, FGF9, LIF, and SCF improve testis cord formation while RA enhances gonocyte survival

• Main Authors: Awang-Junaidi, Awang Hazmi, Fayaz, Mohammad Amin, Goldstein, Savannah, Honaramooz, Ali
• Format: Article
• Published: Springer 2022
• Online Access: http://psasir.upm.edu.my/id/eprint/102560/; https://link.springer.com/article/10.1007/s00441-022-03641-w

Implantation of testis cell aggregates from various donors under the back skin of recipient mice results in de novo formation of testis tissue. We used this implantation model to study the putative in vivo effects of six different growth factors on testis cord development. Recipient mice (n = 7/grou...