Interleukin-27 disrupts the crosstalk of apoptotic activities between 4T1 breast cancer cells and M2 macrophages

• Main Authors: Mohd Yusof, Nurliyana, Mohamed Noor Fuadi, Natasha Nurafiqah, Hamid, Muhajir, Mohammed Alitheen, Noorjahan Banu, Mohd Hanafi, Nursyuhaida, Nik Abd Rahman, Nik Mohd Afizan
• Format: Article
• Published: Universiti Putra Malaysia Press 2022
• Online Access: http://psasir.upm.edu.my/id/eprint/101959/; https://medic.upm.edu.my/jurnal_kami/volume_18_2022/mjmhs_vol18_no_6_november_2022-70224

Introduction: Cytokine immunotherapy such as Interleukin-27 (IL-27) has been foreseen as a promising alternative anti-cancer treatment. Thus, this study aimed to investigate whether IL-27 gene therapy regulates crosstalk between breast cancer cells and macrophages in the sense of pro-apoptotic activ...