In silico prediction of deleterious single nucleotide polymorphism in S100A4 metastatic gene: potential early diagnostic marker

• Main Authors: Aisha Farhana, ., Kothandan, Sangeetha, Alsrhani, Abdullah, Mok, Pooi Ling, Subbiah, Suresh Kumar, Yusuf Saleem Khan
• Format: Article
• Published: Hindawi 2022
• Online Access: http://psasir.upm.edu.my/id/eprint/101935/; https://www.hindawi.com/journals/cmmi/2022/4202623/

S100A4 protein overexpression has been reported in different types of cancer and plays a key role by interacting with the tumor suppressor protein Tp53. Single nucleotide polymorphisms (SNP) in S100A4 could directly influence the biomolecular interaction with the tumor suppressor protein Tp53 due to...