Designed mini protein 20 mimicking uricase encapsulated in ZIF-8 as nanozyme biosensor for uric acid detection

• Main Authors: Abdul Aziz, Siti Fatimah Nur, Salleh, Abu Bakar, Ashari, Siti Efliza, Normi, Yahaya M., Yusof, Nor Azah, Ahmad, Shahrul Ainliah Alang
• Format: Article
• Published: MDPI 2022
• Online Access: http://psasir.upm.edu.my/id/eprint/100902/; https://www.mdpi.com/2079-4991/12/13/2290

This work presents the use of encapsulated mini protein 20 mimicking uricase (mp20)-zeolitic imidazolate framework-8 (ZIF-8) as a bioreceptor for the development of a nanozyme-based electrochemical biosensor for uric acid detection. The electrochemical performance of the biofunctionalized mp20@ZIF-8...