Surface Topography Steer Soft Tissue Response and Antibacterial Function at the Transmucosal Region of Titanium Implant

• Main Authors: Safaei M., Mohammadi H., Beddu S., Mozaffari H.R., Rezaei R., Sharifi R., Moradpoor H., Fallahnia N., Ebadi M., Jamil M.S.M., Zain A.R.M., Yusop M.R.
• Other Authors: 36612136800
• Format: Review
• Published: Dove Medical Press Ltd 2025
• Subjects: Animals; Anti-Bacterial Agents; Biofilms; Dental Implants; Humans; Metal Nanoparticles; Surface Properties; Titanium; antiinfective agent; metal nanoparticle; silver; titanium; antibacterial activity; antifungal activity; bacterial membrane; biocompatibility; biofilm; bone development; bullock; clinical practice; collagen fiber; connective tissue; cytotoxicity; encapsulation; human; immune response; immunomodulation; immunotherapy; in vitro study; in vivo study; macrophage; microenvironment; nonhuman; osteoporosis; pharmaceutics; pharmacology; phenotype; product development; review; saliva; soft tissue; stretching; tissue reaction; tooth implant; topography; animal; chemistry; drug effect; surface property

Metallic dental implants have been extensively used in clinical practice due to their superior mechanical properties, biocompatibility, and aesthetic outcomes. However, their integration with the surrounding soft tissue at the mucosal region remains challenging and can cause implant failure due to t...