Release behavior and cytotoxicity of captopril-intercalated layered double hydroxide for an antihypertensive drug delivery system

• Main Authors: Jadam M.L., Jubri Z., Sarijo S.H.
• Other Authors: 57193566449
• Format: Article
• Published: Springer 2024
• Subjects: Antihypertensive drug; Captopril; Controlled release; Drug delivery system; Zinc�aluminum-layered double hydroxide; Aluminum compounds; Controlled drug delivery; Drug products; Field emission microscopes; Fourier transform infrared spectroscopy; Nanocomposites; Precipitation (chemical); Targeted drug delivery; Thermogravimetric analysis; Zinc; Antihypertensive drugs; Coprecipitation method; Drug-delivery systems; Layered-double hydroxides; Release behaviors; Zinc aluminiums; Zinc-aluminum; Scanning electron microscopy

Intercalation of an antihypertensive drug, captopril (CPL) into zinc�aluminum-layered (ZAL) double hydroxide carrier was successfully accomplished via co-precipitation method. The resulting material was investigated by powder X-ray diffraction, Fourier transform infrared spectroscopy, thermogravimet...