Study on the Enhancement of Malaysian ICU Centre and Introduction of STAR Performance
Blood; Glucose; Insulin; Intensive care units; Patient treatment; Stars; Stochastic systems; Hyperglycaemia; Hypoglycaemia; Intensive insulin therapies; Performance; Stochastic targeted; Stochastics; Stress induced hyperglycemia; Stress-induced; MATLAB
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Springer Science and Business Media Deutschland GmbH
2023
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my.uniten.dspace-273022023-05-29T17:42:23Z Study on the Enhancement of Malaysian ICU Centre and Introduction of STAR Performance Rosly C.Z. Jamaludin U.K. Khalid K. Suhaimi F. Abdul Razak N.N. Mat Nor M.B. Md Ralib A. 57193915509 55330889600 57193918513 36247893200 37059587300 57226799207 57278164400 Blood; Glucose; Insulin; Intensive care units; Patient treatment; Stars; Stochastic systems; Hyperglycaemia; Hypoglycaemia; Intensive insulin therapies; Performance; Stochastic targeted; Stochastics; Stress induced hyperglycemia; Stress-induced; MATLAB Stress-induced hyperglycaemia commonly occurred in the ICU. It is known that the majority of the ICU centre in Malaysia is using intensive insulin therapy (IIT) protocol in order to control glucose level in critically ill patient blood within the targeted level to achieve required safety goals. However, alterations to the current practice needed to be considered to minimize the risk of hypoglycaemia and mortality while reducing the case of hyperglycaemia event. Therefore, the objective of this research paper is to weigh and evaluate the performance of a modern practice known as Stochastic Targeted (STAR) Protocol in managing blood glucose (BG) levels in Malaysia ICU cohort and to compare its performance between the three participating hospitals (HTAA, HUSM and PPUM) via MATLAB simulations. STAR is a tablet-computer based protocols that provide patient-specific glucose control framework accounting for patient variability with a stochastically derived maximum 5% risk of hypoglycaemia events. The in-silico trials were simulated with controlled goal feed (GF) and without GF. Only one type of nutrition is considered in this study, which is Glucerna. The results show that all three ICU centre with STAR simulation have a tight glycemic control with HTAA (83.6%), HUSM (76.8%) and PPUM (80.6%) in terms of BG within the targeted band of 4.0�10.0�mmol/L. Also, the median BG measurement level and insulin secretion shows decrease in percentage for all ICU cohort, HTAA (12.3%; 30.2%), HUSM (21.6%; 9.9%) and PPUM (17.9%; 13.3%). The insulin sensitivity (SI) of STAR simulations have a significant increase when compared with IIT protocol, HTAA (26.1%), HUSM (33.3%) and PPUM (50%). The Kruskal-Wallis test was utilized to test the BG, SI and insulin secretion median. There are significant differences between IIT protocol and STAR simulations among the three cohorts ICU centre with p-value < 0.05. � 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. Final 2023-05-29T09:42:23Z 2023-05-29T09:42:23Z 2022 Conference Paper 10.1007/978-981-16-4115-2_5 2-s2.0-85116869809 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116869809&doi=10.1007%2f978-981-16-4115-2_5&partnerID=40&md5=02c73ff438c988a15f27d1147cf1789f https://irepository.uniten.edu.my/handle/123456789/27302 63 73 Springer Science and Business Media Deutschland GmbH Scopus |
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| description |
Blood; Glucose; Insulin; Intensive care units; Patient treatment; Stars; Stochastic systems; Hyperglycaemia; Hypoglycaemia; Intensive insulin therapies; Performance; Stochastic targeted; Stochastics; Stress induced hyperglycemia; Stress-induced; MATLAB |
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57193915509 |
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57193915509 Rosly C.Z. Jamaludin U.K. Khalid K. Suhaimi F. Abdul Razak N.N. Mat Nor M.B. Md Ralib A. |
| format |
Conference Paper |
| author |
Rosly C.Z. Jamaludin U.K. Khalid K. Suhaimi F. Abdul Razak N.N. Mat Nor M.B. Md Ralib A. |
| spellingShingle |
Rosly C.Z. Jamaludin U.K. Khalid K. Suhaimi F. Abdul Razak N.N. Mat Nor M.B. Md Ralib A. Study on the Enhancement of Malaysian ICU Centre and Introduction of STAR Performance |
| author_sort |
Rosly C.Z. |
| title |
Study on the Enhancement of Malaysian ICU Centre and Introduction of STAR Performance |
| title_short |
Study on the Enhancement of Malaysian ICU Centre and Introduction of STAR Performance |
| title_full |
Study on the Enhancement of Malaysian ICU Centre and Introduction of STAR Performance |
| title_fullStr |
Study on the Enhancement of Malaysian ICU Centre and Introduction of STAR Performance |
| title_full_unstemmed |
Study on the Enhancement of Malaysian ICU Centre and Introduction of STAR Performance |
| title_sort |
study on the enhancement of malaysian icu centre and introduction of star performance |
| publisher |
Springer Science and Business Media Deutschland GmbH |
| publishDate |
2023 |
| _version_ |
1806426664021786624 |
| score |
13.211869 |