Propolis efficacy on SARS-COV viruses: a review on antimicrobial activities and molecular simulations
antimicrobial activity; bee; COVID-19; literature review; mortality; severe acute respiratory syndrome; simulation; vaccine; virus; antiinflammatory agent; antivirus agent; biological product; propolis; drug therapy; human; Anti-Inflammatory Agents; Antiviral Agents; Biological Products; COVID-19; C...
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Springer Science and Business Media Deutschland GmbH
2023
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my.uniten.dspace-268112023-05-29T17:36:53Z Propolis efficacy on SARS-COV viruses: a review on antimicrobial activities and molecular simulations Ghosh S. Al-Sharify Z.T. Maleka M.F. Onyeaka H. Maleke M. Maolloum A. Godoy L. Meskini M. Rami M.R. Ahmadi S. Al-Najjar S.Z. Al-Sharify N.T. Ahmed S.M. Dehghani M.H. 57192654713 57204908487 55654685900 6506961237 56466035200 57786611400 57224821418 57202514280 57212216439 57710506700 57218553613 57205364615 57696704100 57192214256 antimicrobial activity; bee; COVID-19; literature review; mortality; severe acute respiratory syndrome; simulation; vaccine; virus; antiinflammatory agent; antivirus agent; biological product; propolis; drug therapy; human; Anti-Inflammatory Agents; Antiviral Agents; Biological Products; COVID-19; COVID-19 Vaccines; Humans; Propolis; SARS-CoV-2 This current study review provides a brief review of a natural bee product known as propolis and its relevance toward combating SARS-CoV viruses. Propolis has been utilized in medicinal products for centuries due to its excellent biological properties. These include anti-oxidant, immunomodulatory, anti-inflammatory, anti-viral, anti-fungal, and bactericidal activities. Furthermore, studies on molecular simulations show that flavonoids in propolis may reduce viral replication. While further research is needed to validate this theory, it has been observed that COVID-19 patients receiving propolis show earlier viral clearance, enhanced symptom recovery, quicker discharge from hospitals, and a reduced mortality rate relative to other patients. As a result, it appears that propolis could probably be useful in the treatment of SARS-CoV-2-infected patients. Therefore, this review sought to explore the natural properties of propolis and further evaluated past studies that investigated propolis as an alternative product for the treatment of COVID-19 symptoms. In addition, the review also highlights the possible mode of propolis action as well as molecular simulations of propolis compounds that may interact with the SARS-CoV-2 virus. The activity of propolis compounds in decreasing the impact of COVID-19-related comorbidities, the possible roles of such compounds as COVID-19 vaccine adjuvants, and the use of nutraceuticals in COVID-19 treatment, instead of pharmaceuticals, has also been discussed. � 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. Final 2023-05-29T09:36:53Z 2023-05-29T09:36:53Z 2022 Review 10.1007/s11356-022-21652-6 2-s2.0-85133616080 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85133616080&doi=10.1007%2fs11356-022-21652-6&partnerID=40&md5=cd1a95335a8c42f891c58f1108046182 https://irepository.uniten.edu.my/handle/123456789/26811 29 39 58628 58647 All Open Access, Bronze, Green Springer Science and Business Media Deutschland GmbH Scopus |
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antimicrobial activity; bee; COVID-19; literature review; mortality; severe acute respiratory syndrome; simulation; vaccine; virus; antiinflammatory agent; antivirus agent; biological product; propolis; drug therapy; human; Anti-Inflammatory Agents; Antiviral Agents; Biological Products; COVID-19; COVID-19 Vaccines; Humans; Propolis; SARS-CoV-2 |
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57192654713 |
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57192654713 Ghosh S. Al-Sharify Z.T. Maleka M.F. Onyeaka H. Maleke M. Maolloum A. Godoy L. Meskini M. Rami M.R. Ahmadi S. Al-Najjar S.Z. Al-Sharify N.T. Ahmed S.M. Dehghani M.H. |
| format |
Review |
| author |
Ghosh S. Al-Sharify Z.T. Maleka M.F. Onyeaka H. Maleke M. Maolloum A. Godoy L. Meskini M. Rami M.R. Ahmadi S. Al-Najjar S.Z. Al-Sharify N.T. Ahmed S.M. Dehghani M.H. |
| spellingShingle |
Ghosh S. Al-Sharify Z.T. Maleka M.F. Onyeaka H. Maleke M. Maolloum A. Godoy L. Meskini M. Rami M.R. Ahmadi S. Al-Najjar S.Z. Al-Sharify N.T. Ahmed S.M. Dehghani M.H. Propolis efficacy on SARS-COV viruses: a review on antimicrobial activities and molecular simulations |
| author_sort |
Ghosh S. |
| title |
Propolis efficacy on SARS-COV viruses: a review on antimicrobial activities and molecular simulations |
| title_short |
Propolis efficacy on SARS-COV viruses: a review on antimicrobial activities and molecular simulations |
| title_full |
Propolis efficacy on SARS-COV viruses: a review on antimicrobial activities and molecular simulations |
| title_fullStr |
Propolis efficacy on SARS-COV viruses: a review on antimicrobial activities and molecular simulations |
| title_full_unstemmed |
Propolis efficacy on SARS-COV viruses: a review on antimicrobial activities and molecular simulations |
| title_sort |
propolis efficacy on sars-cov viruses: a review on antimicrobial activities and molecular simulations |
| publisher |
Springer Science and Business Media Deutschland GmbH |
| publishDate |
2023 |
| _version_ |
1806426141277290496 |
| score |
13.18916 |