New insights of phenolic compounds from optimized fruit extract of Ficus auriculata
antioxidant; phenol derivative; plant extract; solvent; centrifugation; chemistry; Ficus; filtration; fruit; isolation and purification; ultrasound; Antioxidants; Centrifugation; Ficus; Filtration; Fruit; Phenols; Plant Extracts; Solvents; Ultrasonic Waves
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Nature Research
2023
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my.uniten.dspace-258892023-05-29T17:05:26Z New insights of phenolic compounds from optimized fruit extract of Ficus auriculata Shahinuzzaman M. Akhtar P. Amin N. Ahmed Y. Anuar F.H. Misran H. Akhtaruzzaman M. 57193799716 56419672800 7102424614 14832383900 57216729900 6506899840 57195441001 antioxidant; phenol derivative; plant extract; solvent; centrifugation; chemistry; Ficus; filtration; fruit; isolation and purification; ultrasound; Antioxidants; Centrifugation; Ficus; Filtration; Fruit; Phenols; Plant Extracts; Solvents; Ultrasonic Waves In this study, the extraction conditions extracted maximize amounts of phenolic and bioactive compounds from the fruit extract of Ficus auriculata by using optimized response surface methodology. The antioxidant capacity was evaluated through the assay of radical scavenging ability on DPPH and ABTS as well as reducing power assays on total phenolic content (TPC). For the extraction purpose, the ultrasonic assisted extraction technique was employed. A second-order polynomial model satisfactorily fitted to the experimental findings concerning antioxidant activity (R2 = 0.968, P < 0.0001) and total phenolic content (R2 = 0.961, P < 0.0001), indicating a significant correlation between the experimental and expected value. The highest DPPH radical scavenging activity was achieved 85.20 � 0.96% at the optimum extraction parameters of 52.5% ethanol (v/v), 40.0��C temperature, and 22�min extraction time. Alternatively, the highest yield of total phenolic content was found 31.65 � 0.94�mg GAE/g DF at the optimum extraction conditions. From the LC�ESI�MS profiling of the optimized extract, 18 bioactive compounds were tentatively identified, which may regulate the antioxidant activity of fruits of F. auriculata. � 2021, The Author(s). Final 2023-05-29T09:05:26Z 2023-05-29T09:05:26Z 2021 Article 10.1038/s41598-021-91913-w 2-s2.0-85108007494 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108007494&doi=10.1038%2fs41598-021-91913-w&partnerID=40&md5=a836b96432b349c7780cecda50858613 https://irepository.uniten.edu.my/handle/123456789/25889 11 1 12503 All Open Access, Gold, Green Nature Research Scopus |
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| description |
antioxidant; phenol derivative; plant extract; solvent; centrifugation; chemistry; Ficus; filtration; fruit; isolation and purification; ultrasound; Antioxidants; Centrifugation; Ficus; Filtration; Fruit; Phenols; Plant Extracts; Solvents; Ultrasonic Waves |
| author2 |
57193799716 |
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57193799716 Shahinuzzaman M. Akhtar P. Amin N. Ahmed Y. Anuar F.H. Misran H. Akhtaruzzaman M. |
| format |
Article |
| author |
Shahinuzzaman M. Akhtar P. Amin N. Ahmed Y. Anuar F.H. Misran H. Akhtaruzzaman M. |
| spellingShingle |
Shahinuzzaman M. Akhtar P. Amin N. Ahmed Y. Anuar F.H. Misran H. Akhtaruzzaman M. New insights of phenolic compounds from optimized fruit extract of Ficus auriculata |
| author_sort |
Shahinuzzaman M. |
| title |
New insights of phenolic compounds from optimized fruit extract of Ficus auriculata |
| title_short |
New insights of phenolic compounds from optimized fruit extract of Ficus auriculata |
| title_full |
New insights of phenolic compounds from optimized fruit extract of Ficus auriculata |
| title_fullStr |
New insights of phenolic compounds from optimized fruit extract of Ficus auriculata |
| title_full_unstemmed |
New insights of phenolic compounds from optimized fruit extract of Ficus auriculata |
| title_sort |
new insights of phenolic compounds from optimized fruit extract of ficus auriculata |
| publisher |
Nature Research |
| publishDate |
2023 |
| _version_ |
1806423427554213888 |
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13.214268 |