The Effects of Insulin Infusion Protocol on the Glycemic Level of the Intensive Care Patients

Digital storage; Glucose; Insulin; Critical care; Glycemic control; HUSM; Insulin infusions; Intensive-care patients; Malaysia; Model-based glycemic control; Model-based OPC; Standard protocols; Intensive care units

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Main Authors: Zukhi J., Suhaimi F.M., Mazlan M.Z., Jamaludin U.K., Razak N., Sopian M.M.
Other Authors: 57194705279
Format: Conference Paper
Published: Elsevier B.V. 2023
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spelling my.uniten.dspace-256162023-05-29T16:11:45Z The Effects of Insulin Infusion Protocol on the Glycemic Level of the Intensive Care Patients Zukhi J. Suhaimi F.M. Mazlan M.Z. Jamaludin U.K. Razak N. Sopian M.M. 57194705279 36247893200 57192209115 55330889600 37059587300 57202639393 Digital storage; Glucose; Insulin; Critical care; Glycemic control; HUSM; Insulin infusions; Intensive-care patients; Malaysia; Model-based glycemic control; Model-based OPC; Standard protocols; Intensive care units Insulin infusion protocol is the standard protocol that has been practiced in Malaysia's intensive care unit (ICU) for controlling the hyperglycemia. Multiple sliding scale method of the insulin infusion protocol may drive conflict in selecting an appropriate scale to be applied to the patient. The objective of this paper is to analyse the blood glucose outcome of eight sliding scales insulin infusion protocol adopted in the Universiti Sains Malaysia Hospital (HUSM). A retrospective data of 78 ICU patients of HUSM were fitted using a validated glucose-insulin system to identify insulin sensitivity profiles of the patients. Then, these SI profiles were simulated on various scale protocols. The results obtained from this study showed that among eight scales, Scale 4 had the highest percentage of BG within the HUSM's target of 6.0-10.0 mmol/L. Scale 1 had the highest percentage of BG for the BG measurement more than 10.0 mmol/L while Scale 8 had the highest percentage of BG measurement of less than 6.0 mmol/L. However, none of the scale shown better performance than the current clinical practice. Furthermore, all of the eight scales had a more substantial number of BG measurement compared to the clinical. This study shows that Scale 2 and Scale 3 result in a similar outcome. Similarly, Scale 5 is almost the same as Scale 6. Thus, at least two sets of scale can be combined to reduce the number of scales. The reduction of scales consequently avoid confusion and helps the clinician in selecting the appropriate scale to be applied to the patients. From this study, it can be concluded that the HUSM protocol is a combination of scales. The scales may be shifted from one to another scale depending on patient condition and clinician judgement. A proper guideline for the scale shifting seems necessary to allow optimum glycemic management in the ICU. � 2020 Elsevier B.V.. All rights reserved. Final 2023-05-29T08:11:45Z 2023-05-29T08:11:45Z 2020 Conference Paper 10.1016/j.ifacol.2020.12.377 2-s2.0-85119962534 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119962534&doi=10.1016%2fj.ifacol.2020.12.377&partnerID=40&md5=39d4073a79d53f9a6b4cf2946730d3f6 https://irepository.uniten.edu.my/handle/123456789/25616 53 2 15964 15969 All Open Access, Bronze Elsevier B.V. Scopus
institution Universiti Tenaga Nasional
building UNITEN Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Tenaga Nasional
content_source UNITEN Institutional Repository
url_provider http://dspace.uniten.edu.my/
description Digital storage; Glucose; Insulin; Critical care; Glycemic control; HUSM; Insulin infusions; Intensive-care patients; Malaysia; Model-based glycemic control; Model-based OPC; Standard protocols; Intensive care units
author2 57194705279
author_facet 57194705279
Zukhi J.
Suhaimi F.M.
Mazlan M.Z.
Jamaludin U.K.
Razak N.
Sopian M.M.
format Conference Paper
author Zukhi J.
Suhaimi F.M.
Mazlan M.Z.
Jamaludin U.K.
Razak N.
Sopian M.M.
spellingShingle Zukhi J.
Suhaimi F.M.
Mazlan M.Z.
Jamaludin U.K.
Razak N.
Sopian M.M.
The Effects of Insulin Infusion Protocol on the Glycemic Level of the Intensive Care Patients
author_sort Zukhi J.
title The Effects of Insulin Infusion Protocol on the Glycemic Level of the Intensive Care Patients
title_short The Effects of Insulin Infusion Protocol on the Glycemic Level of the Intensive Care Patients
title_full The Effects of Insulin Infusion Protocol on the Glycemic Level of the Intensive Care Patients
title_fullStr The Effects of Insulin Infusion Protocol on the Glycemic Level of the Intensive Care Patients
title_full_unstemmed The Effects of Insulin Infusion Protocol on the Glycemic Level of the Intensive Care Patients
title_sort effects of insulin infusion protocol on the glycemic level of the intensive care patients
publisher Elsevier B.V.
publishDate 2023
_version_ 1806428298816782336
score 13.214268