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Dynamic mechanical analysis of polyethylene terephthalate/hydroxyapatite biocomposites for tissue engineering applications

Biocompatibility; Biomaterials; Biomechanics; Composite materials; Dichloromethane; Dynamics; Functional polymers; Hydroxyapatite; Morphology; Polyethylene terephthalates; Polyethylenes; Scaffolds (biology); Scanning electron microscopy; Tissue; Tissue engineering; Dynamic mechanical analysis (DMA);...

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Main Authors: Sughanthy S.A.P., Ansari M.N.M., Atiqah A.
Other Authors: 57205239893
Format: Article
Published: Elsevier Editora Ltda 2023
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spelling my.uniten.dspace-255602023-05-29T16:10:55Z Dynamic mechanical analysis of polyethylene terephthalate/hydroxyapatite biocomposites for tissue engineering applications Sughanthy S.A.P. Ansari M.N.M. Atiqah A. 57205239893 55489853600 55366998300 Biocompatibility; Biomaterials; Biomechanics; Composite materials; Dichloromethane; Dynamics; Functional polymers; Hydroxyapatite; Morphology; Polyethylene terephthalates; Polyethylenes; Scaffolds (biology); Scanning electron microscopy; Tissue; Tissue engineering; Dynamic mechanical analysis (DMA); Engineering polymers; Nano bio composites; Nanofibrous scaffolds; Polyethylene terephthalates (PET); Synthetic biomaterials; Thermomechanical properties; Tissue engineering applications; Plastic bottles Synthetic biomaterials are widely used for the treatment of diseased or damaged tissue in the field of tissue engineering. Polyethylene terephthalate (PET) is a synthetic thermoplastic engineering polymer with high commercial and industrial interest and has been widely used as implant material in biomedical engineering. Despite that, PET has limited applications due to its high hydrophobicity. Hydroxyapatite (HA) is one of the known biocompatible ceramic for the development of porous scaffolds for bone replacement and tissue engineering due to its resemblance to the mineral constituents of human bones and teeth. Therefore, HA was functionalized into the PET matrix in order to improve the limitation. In this research, PET-HA nano-biocomposite scaffold was electrospun using the electrospinning system. PET and HA were dissolved using trifluoroacetic acid (TFA) and dichloromethane (DCM). The nanofibrous scaffolds were produced at optimum process parameters. The morphology studies were performed using a Scanning Electron Microscope (SEM) and thermomechanical properties were evaluated using Dynamic Mechanical Analysis (DMA). From the morphology analysis, PET-HA nano-biocomposite scaffold which composed of 96% of PET and 4% of HA, has obtained the largest fiber diameter. The DMA analysis showed that the addition of HA improved mechanical properties. However, PET-HA nano-biocomposite scaffold composed of 98% of PET and 2% of HA was preferred as it has the lower value of storage and loss modulus because the application was focusing on the skin where the more flexible scaffold was needed. The PET-HA nano-biocomposite scaffold fabricated has good potential to be used in tissue engineering applications. � 2019 The Authors. Final 2023-05-29T08:10:55Z 2023-05-29T08:10:55Z 2020 Article 10.1016/j.jmrt.2019.12.066 2-s2.0-85078731187 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85078731187&doi=10.1016%2fj.jmrt.2019.12.066&partnerID=40&md5=230f6f3234471dc12c620e2d376c1141 https://irepository.uniten.edu.my/handle/123456789/25560 9 2 2350 2356 All Open Access, Gold Elsevier Editora Ltda Scopus
institution Universiti Tenaga Nasional
building UNITEN Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Tenaga Nasional
content_source UNITEN Institutional Repository
url_provider http://dspace.uniten.edu.my/
description Biocompatibility; Biomaterials; Biomechanics; Composite materials; Dichloromethane; Dynamics; Functional polymers; Hydroxyapatite; Morphology; Polyethylene terephthalates; Polyethylenes; Scaffolds (biology); Scanning electron microscopy; Tissue; Tissue engineering; Dynamic mechanical analysis (DMA); Engineering polymers; Nano bio composites; Nanofibrous scaffolds; Polyethylene terephthalates (PET); Synthetic biomaterials; Thermomechanical properties; Tissue engineering applications; Plastic bottles
author2 57205239893
author_facet 57205239893
Sughanthy S.A.P.
Ansari M.N.M.
Atiqah A.
format Article
author Sughanthy S.A.P.
Ansari M.N.M.
Atiqah A.
spellingShingle Sughanthy S.A.P.
Ansari M.N.M.
Atiqah A.
Dynamic mechanical analysis of polyethylene terephthalate/hydroxyapatite biocomposites for tissue engineering applications
author_sort Sughanthy S.A.P.
title Dynamic mechanical analysis of polyethylene terephthalate/hydroxyapatite biocomposites for tissue engineering applications
title_short Dynamic mechanical analysis of polyethylene terephthalate/hydroxyapatite biocomposites for tissue engineering applications
title_full Dynamic mechanical analysis of polyethylene terephthalate/hydroxyapatite biocomposites for tissue engineering applications
title_fullStr Dynamic mechanical analysis of polyethylene terephthalate/hydroxyapatite biocomposites for tissue engineering applications
title_full_unstemmed Dynamic mechanical analysis of polyethylene terephthalate/hydroxyapatite biocomposites for tissue engineering applications
title_sort dynamic mechanical analysis of polyethylene terephthalate/hydroxyapatite biocomposites for tissue engineering applications
publisher Elsevier Editora Ltda
publishDate 2023
_version_ 1806424039108902912
score 13.211869

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