Study on the blood glucose management with controlled goal feed in Malaysian critically ill patients
Blood; Glucose; Insulin; Medical computing; mHealth; Nutrition; Physiological models; Stars; Stochastic systems; Blood glucose level; Blood glucose management; Critically-ill patients; Current practices; Diabetes patients; Intensive insulin therapies; Patient specific; Virtual patients; Intensive ca...
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2023
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my.uniten.dspace-248202023-05-29T15:27:31Z Study on the blood glucose management with controlled goal feed in Malaysian critically ill patients Zafirah R.C. Ummu K.J. Khalijah K. Luqman H.M. Aishah A.F.Q.A. Azrina R. Basri M.N.M. Fatanah S. Normy N.A.R. 57205656815 55330889600 57204801654 57193665267 57205656933 57205661976 55497505200 57205662962 57205660433 Blood; Glucose; Insulin; Medical computing; mHealth; Nutrition; Physiological models; Stars; Stochastic systems; Blood glucose level; Blood glucose management; Critically-ill patients; Current practices; Diabetes patients; Intensive insulin therapies; Patient specific; Virtual patients; Intensive care units Stress-induced hyperglycaemia is commonly occurred in the intensive care unit (ICU). It is known that the intensive insulin therapy (IIT) has successfully managed the blood glucose level within the targeted band. However, modifications on the current practice need to be considered to minimize the risk of hypoglycaemia and mortality. Thus, the aim of this study is to assess the performance of a new practice known as Stochastic Targeted (STAR) Protocol in managing blood glucose levels in Malaysia ICU setting. STAR is a tablet-computer based protocols that provides patient-specific glucose control framework accounting for patient variability with a stochastically derived maximum 5% risk of hypoglycaemia events. A retrospective 92 non-diabetes patient's data who underwent IIT were identified. Patient's blood glucose levels, exogenous insulin and nutrition inputs including patient demographics were extracted from the ICU charts to create virtual patients by using physiologically mathematical model. Three trials were simulated with controlled goal feed (GF) and without GF. Only one type of nutrition is considered in this study which is Glucerna. The outcomes will be compared in terms of %BG within the targeted band of 4.4 to 10.0 mmol/L, the total number of BG measurements, and the % of severe hypoglycaemia. The results indicate that STAR virtual trial with controlled GF reduced the risk of hypoglycaemia to 3% and the clinical burden up to 1630 hours while maintaining BG within the targeted band. The total number of BG measurements also decreased to 5384 from 7038. Thus, the implementation of STAR protocol in the Malaysia ICU is beneficial and it is proven safe while aiding nurses and physicians in reducing the clinical burden and medical cost in treating stress-induce hyperglycaemia in the demanding ICU setting. � Published under licence by IOP Publishing Ltd. Final 2023-05-29T07:27:31Z 2023-05-29T07:27:31Z 2019 Conference Paper 10.1088/1757-899X/469/1/012097 2-s2.0-85061000863 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061000863&doi=10.1088%2f1757-899X%2f469%2f1%2f012097&partnerID=40&md5=70306a07ec86f2654809958899b935b8 https://irepository.uniten.edu.my/handle/123456789/24820 469 1 12097 All Open Access, Gold Institute of Physics Publishing Scopus |
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Blood; Glucose; Insulin; Medical computing; mHealth; Nutrition; Physiological models; Stars; Stochastic systems; Blood glucose level; Blood glucose management; Critically-ill patients; Current practices; Diabetes patients; Intensive insulin therapies; Patient specific; Virtual patients; Intensive care units |
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57205656815 |
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57205656815 Zafirah R.C. Ummu K.J. Khalijah K. Luqman H.M. Aishah A.F.Q.A. Azrina R. Basri M.N.M. Fatanah S. Normy N.A.R. |
| format |
Conference Paper |
| author |
Zafirah R.C. Ummu K.J. Khalijah K. Luqman H.M. Aishah A.F.Q.A. Azrina R. Basri M.N.M. Fatanah S. Normy N.A.R. |
| spellingShingle |
Zafirah R.C. Ummu K.J. Khalijah K. Luqman H.M. Aishah A.F.Q.A. Azrina R. Basri M.N.M. Fatanah S. Normy N.A.R. Study on the blood glucose management with controlled goal feed in Malaysian critically ill patients |
| author_sort |
Zafirah R.C. |
| title |
Study on the blood glucose management with controlled goal feed in Malaysian critically ill patients |
| title_short |
Study on the blood glucose management with controlled goal feed in Malaysian critically ill patients |
| title_full |
Study on the blood glucose management with controlled goal feed in Malaysian critically ill patients |
| title_fullStr |
Study on the blood glucose management with controlled goal feed in Malaysian critically ill patients |
| title_full_unstemmed |
Study on the blood glucose management with controlled goal feed in Malaysian critically ill patients |
| title_sort |
study on the blood glucose management with controlled goal feed in malaysian critically ill patients |
| publisher |
Institute of Physics Publishing |
| publishDate |
2023 |
| _version_ |
1806426515388235776 |
| score |
13.223943 |