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Blood glucose and sepsis score on sepsis patients requiring insulin therapy

Biomedical engineering; Blood; Diagnosis; Glucose; Insulin; Blood glucose; Blood glucose level; Clinical guideline; Insulin sensitivity; Insulin therapy; Patient condition; Provide guidances; Sepsis; Patient treatment

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Bibliographic Details
Main Authors: Mohamad Suhaimi F., Jamaludin U.K., Abdul Razak N.N., Pretty C.G., Md. Ralib A., Mat Nor M.B., Dzaharudin F.
Other Authors: 36247893200
Format: Conference Paper
Published: Springer Verlag 2023
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spelling my.uniten.dspace-242272023-05-29T14:57:11Z Blood glucose and sepsis score on sepsis patients requiring insulin therapy Mohamad Suhaimi F. Jamaludin U.K. Abdul Razak N.N. Pretty C.G. Md. Ralib A. Mat Nor M.B. Dzaharudin F. 36247893200 55330889600 37059587300 6508290605 37031770900 57226799207 35219916100 Biomedical engineering; Blood; Diagnosis; Glucose; Insulin; Blood glucose; Blood glucose level; Clinical guideline; Insulin sensitivity; Insulin therapy; Patient condition; Provide guidances; Sepsis; Patient treatment Early treatment of sepsis is crucial in improving the patient condition and reduces mortality. The lack of information and methods to diagnose sepsis at an early stage is a significant barrier to early treatment. Treatment is normally based on clinical judgment since blood cultures are negative in the majority of sepsis or septic shock cases as reported in several studies. Even with blood cultures result, a delay in diagnosis may happen while waiting for the results. Therefore, clinical guidelines are still required to provide guidance for the clinician caring for a patient with severe sepsis or septic shock. In this study, a validated glucose-insulin model is used to capture patient-specific insulin sensitivity profile. The validated model is incorporated with a sepsis system to create a glucose-insulin model that describe sepsis occurrence. The relationship between insulin sensitivity, blood glucose and sepsis score is investigated using a retrospective data of 8 patients admitted in the Tengku Ampuan Afzan Hospital, Kuantan. Results indicate that there was a significant relationship between blood glucose level and sepsis score (p�<�0.001), and insulin sensitivity with a sepsis score (p�<�0.001). Additionally, blood glucose level was higher in a severe sepsis group compared to the non-sepsis group. Whereas, insulin sensitivity is lower in a severe sepsis group. Insulin sensitivity profile can be incorporated with the sepsis system for monitoring sepsis patients requiring insulin therapy as seen in this study. Thus, the sepsis glucose-insulin model can potentially be used as an indicator or tools for sepsis diagnosis. � 2018, Springer Science+Business Media Singapore. Final 2023-05-29T06:57:11Z 2023-05-29T06:57:11Z 2018 Conference Paper 10.1007/978-981-10-7554-4_46 2-s2.0-85038128429 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85038128429&doi=10.1007%2f978-981-10-7554-4_46&partnerID=40&md5=93dc32c3a5d2e1fbf709d67e7ec27776 https://irepository.uniten.edu.my/handle/123456789/24227 67 265 269 Springer Verlag Scopus
institution Universiti Tenaga Nasional
building UNITEN Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Tenaga Nasional
content_source UNITEN Institutional Repository
url_provider http://dspace.uniten.edu.my/
description Biomedical engineering; Blood; Diagnosis; Glucose; Insulin; Blood glucose; Blood glucose level; Clinical guideline; Insulin sensitivity; Insulin therapy; Patient condition; Provide guidances; Sepsis; Patient treatment
author2 36247893200
author_facet 36247893200
Mohamad Suhaimi F.
Jamaludin U.K.
Abdul Razak N.N.
Pretty C.G.
Md. Ralib A.
Mat Nor M.B.
Dzaharudin F.
format Conference Paper
author Mohamad Suhaimi F.
Jamaludin U.K.
Abdul Razak N.N.
Pretty C.G.
Md. Ralib A.
Mat Nor M.B.
Dzaharudin F.
spellingShingle Mohamad Suhaimi F.
Jamaludin U.K.
Abdul Razak N.N.
Pretty C.G.
Md. Ralib A.
Mat Nor M.B.
Dzaharudin F.
Blood glucose and sepsis score on sepsis patients requiring insulin therapy
author_sort Mohamad Suhaimi F.
title Blood glucose and sepsis score on sepsis patients requiring insulin therapy
title_short Blood glucose and sepsis score on sepsis patients requiring insulin therapy
title_full Blood glucose and sepsis score on sepsis patients requiring insulin therapy
title_fullStr Blood glucose and sepsis score on sepsis patients requiring insulin therapy
title_full_unstemmed Blood glucose and sepsis score on sepsis patients requiring insulin therapy
title_sort blood glucose and sepsis score on sepsis patients requiring insulin therapy
publisher Springer Verlag
publishDate 2023
_version_ 1806427654048448512
score 13.188404

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