Validation and utilization of an internally controlled multiplex Real-time RT-PCR assay for simultaneous detection of enteroviruses and enterovirus A71 associated with hand foot and mouth disease

• Main Authors: Thanh, Tran Tan, Anh, Nguyen To, Tham, Nguyen Thi, Van, Hoang Minh Tu, Sabanathan, Saraswathy, Qui, Phan Tu, Ngan, Tran Thuy, Van, Tran Thi My, Nguyen, Thi Han Ny, Thanh, Le Thi My, Chai, Ong Kien, Perera, David, Viet, Do Chau, Khanh, Truong Huu, Ha, Do Quang, Tuan, Ha Manh, Wong, Kum Thong, Hung, Nguyen Thanh, Chau, Nguyen Van Vinh, Thwaites, Guy, Doorn, H. Rogier van, Tan, Le Van
• Format: Article
• Language: English
• Published: BioMed Central 2015
• Subjects: Q Science (General); QR355 Virology; R Medicine (General); RJ Pediatrics
• Online Access: http://ir.unimas.my/id/eprint/8723/1/Thanh.pdf; http://ir.unimas.my/id/eprint/8723/; http://www.virologyj.com/content/12/1/85

Background: Hand foot and mouth disease (HFMD) is a disease of public health importance across the Asia-Pacific region. The disease is caused by enteroviruses (EVs), in particular enterovirus A71 (EV-A71). In EV-A71-associated HFMD, the infection is sometimes associated with severe manifestations...