Co-expression of citrulline-nitric oxide cycle enzymes and decreased glutamine synthetase expression in different regions of brain in epilepsy rat model

• Main Authors: Swamy, Mummedy, Wan Yusof, Wan Roslina, Mat Zin, Intan Nurfirdaus, Sirajudeen, K. N. S., Mustapha, Zulkarnain, Govindasamy, Chandran
• Format: E-Article
• Language: English
• Published: Academic Journal 2011
• Subjects: QD Chemistry; RM Therapeutics. Pharmacology
• Online Access: http://ir.unimas.my/id/eprint/693/1/Co-expression%20of%20citrulline-nitric%20oxide%20cycle%20enzymes%28abstract%29.pdf; http://ir.unimas.my/id/eprint/693/; http://www/academicjournals.org/AJPP

The aim of this study was to determine the mRNA expression of nitric oxide synthetase (NOS), argininosuccinate synthetase (AS), argininosuccinate lyase (AL) and glutamine synthetase (GS) in different regions of brain in rats subjected to kainic acid (KA) mediated epilepsy. The short term (acute) gro...