In Enterovirus 71 Encephalitis With Cardio-Respiratory Compromise, Elevated Interleukin 1β, Interleukin 1 Receptor Antagonist, and Granulocyte Colony-Stimulating Factor Levels Are Markers of Poor Prognosis

• Main Authors: Griffiths, Michael J., Ooi, Mong H., Wong, See Chang, Mohan, Anand, Podin, Yuwana, Perera, David, Chieng, Chae H., Tio, Phaik Hooi, Cardosa, Mary Jane, Solomon, Tom
• Format: E-Article
• Language: English
• Published: Oxford Journals 2012
• Subjects: Q Science (General); QR180 Immunology; QR355 Virology; R Medicine (General)
• Online Access: http://ir.unimas.my/id/eprint/6695/1/In%20Enterovirus%2071%20Encephalitis%20With%20Cardio-respiratory%20%28abstract%29.pdf; http://ir.unimas.my/id/eprint/6695/; http://jid.oxfordjournals.org/content/206/6/881.long

Background. Enterovirus 71 (EV71) causes large outbreaks of hand, foot, and mouth disease (HFMD), with severe neurological complications and cardio-respiratory compromise, but the pathogenesis is poorly understood. Methods. We measured levels of 30 chemokines and cytokines in serum and cerebrospi...