Regulation of G protein signaling by the 70 kDa heat shock protein

• Main Authors: William K., Lim, Kimon C., Kanelakis, Richard R., Neubig
• Format: Article
• Language: English
• Published: Elsevier B.V. 2013
• Subjects: RM Therapeutics. Pharmacology
• Online Access: http://ir.unimas.my/id/eprint/45710/1/Regulation%20of%20G%20protein%20signaling%20-%20Copy.pdf; http://ir.unimas.my/id/eprint/45710/; https://www.sciencedirect.com/science/article/abs/pii/S0898656812003051; https://doi.org/10.1016/j.cellsig.2012.11.002

G protein-coupled receptors (GPCRs) transduce extracellular signals to the interior of the cell by activating membrane-bound guanine nucleotide-binding regulatory proteins (G proteins). An increasing number of proteins have been reported to bind to and regulate GPCRs. We report a novel regulation...