Phytochemical Profiling of Garcinia rostrata, Garcinia dryobalanosides and Garcinia cuneifolia and Their Antibacterial Activity
Garcinia spp. have been used in traditional medicine to treat various ailments, and recent studies have confirmed their pharmacological activities. In this context, the present study focused on three Garcinia spp., namely Garcinia rostrata, Garcinia dryobalanoides and Garcinia cuneifolia, which gai...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
UNIMAS Publisher
2024
|
| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/45118/3/Phytochemical%20Profiling%20of%20Garcinia%20-%20Copy.pdf http://ir.unimas.my/id/eprint/45118/ https://publisher.unimas.my/ojs/index.php/BJRST/article/view/5672 https:doi.org/10.33736/bjrst.5672.2024 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Garcinia spp. have been used in traditional medicine to treat various ailments, and recent studies have confirmed
their pharmacological activities. In this context, the present study focused on three Garcinia spp., namely Garcinia rostrata, Garcinia dryobalanoides and Garcinia cuneifolia, which gain less attention in terms of their
phytoconstituent and biological activity data. Methodologically, in this study, the phytochemical constituents of the three Garcinia sp. was determined through gas chromatography mass spectrometry (GC-MS) whereby the
antimicrobial activity was evaluated using the Disc diffusion and Dilution method. The results showed that the
extract from Garcinia dryobalanoides exhibited the most potent antibacterial activity against Bacillus
amyloliquefaciens compared to the other species. The phytochemical analysis found that Garcinia dryobalanoides
extract contained significant amounts of (Z)-18-Octadec-9-enolide and n-hexadecanoic acid, which are known to
possess antibacterial properties. These major constituents were found to interact synergistically to produce the
observed antibacterial activity. The findings suggested that Garcinia dryobalanoides could be a promising source
for developing new antibiotics to combat bacterial infections. Overall, this study highlights the potential of
Garcinia spp. for discovering new bioactivities, particularly their antibacterial properties. Further research is needed to explore the full range of phytochemical constituents and biological activities of these plants, which could lead to the development of new drugs to combat antibiotic resistance. |
|---|