Cost-effective complete genome sequencing using the MinION platform for identification of recombinant enteroviruses

• Main Authors: Chien, Yeh Seng, Chen, Feng Jui, Wu, Han Chieh, Lin, Chieh Hua, Chang, Wen Chiung, David, Perera, Yang, Jyh Yuan, Lee, Min Shi, Liao, Yu Chieh
• Format: Article
• Language: English
• Published: American Society for Microbiology 2023
• Subjects: Q Science (General); QR355 Virology; R Medicine (General)
• Online Access: http://ir.unimas.my/id/eprint/43592/3/Cost-effective.pdf; http://ir.unimas.my/id/eprint/43592/; https://journals.asm.org/doi/10.1128/spectrum.02507-23

Enteroviruses (EVs) are a group of viruses that cause various human illnesses. While the CODEHOP (COnsensus-DEgenerate Hybrid Oligonucleotide Primer) method can generate VP1 gene fragments for enterovirus genotyping, it is unable to detect recombinant strains. Recent advances in viral genome sequenc...