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Chemically modified water-soluble chitosan derivatives : Modification strategies, biological activities, and applications

Chitosan, a biocompatible and nontoxic heteropolymer derived from chitin, offers various applications. However, its limited solubility above pH 6.5 hinders its broader applications. Chemical, physical, and enzymatic modifications have greatly improved chitosan properties, producing water-soluble chi...

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Bibliographic Details
Main Authors: Wan Roslina, Wan Yusof, Nur Yusra Farzana, Awang, Muhammad Affuwan Azhar, Laile, Juzaili, Azizi, Awang Ahmad Sallehin, Awang Husaini, Azman, Seeni, Lee D., Wilson, Sabar, Sumiyyah, Sumiyyah, Sabar
Format: Article
Language:English
Published: Taylor & Francis 2023
Subjects:
QD Chemistry
Online Access:http://ir.unimas.my/id/eprint/42750/3/Chemically.pdf
http://ir.unimas.my/id/eprint/42750/
https://www.tandfonline.com/doi/abs/10.1080/25740881.2023.2249979
https://doi.org/10.1080/25740881.2023.2249979
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Summary:Chitosan, a biocompatible and nontoxic heteropolymer derived from chitin, offers various applications. However, its limited solubility above pH 6.5 hinders its broader applications. Chemical, physical, and enzymatic modifications have greatly improved chitosan properties, producing water-soluble chitosan (WSC) and derivatives. WSC and its derivatives possess unique structures, properties, and water solubility, meeting the demands of functional materials. This review highlights native chitosan characteristics, modification strategies for WSC and emphasizes its applications in food production, wastewater treatment, biomedical, and agriculture. Future perspectives for WSC and its derivatives are also discussed at the end of this paper.

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