Screening of Medicinal Plants against A. flavus

• Main Author: Syamimi Izzati, Hussin
• Format: Final Year Project Report
• Language: English; English
• Published: Universiti Malaysia Sarawak, (UNIMAS) 2022
• Subjects: RS Pharmacy and materia medica
• Online Access: http://ir.unimas.my/id/eprint/39913/1/SYAMIMI%20IZZATI%20BT%20HUSSIN%2024pgs.pdf; http://ir.unimas.my/id/eprint/39913/2/SYAMIMI%20IZZATI%20BT%20HUSSIN%20ft.pdf; http://ir.unimas.my/id/eprint/39913/

Aspergillus flavus is one of the most common fungi that produce carcinogenic aflatoxins. The plants’ bioactive components were already been used to lower the risk of carcinogenicity and mutagenicity of aflatoxin through inhibition of fungal growth and aflatoxin contamination. Antimicrobial compounds in plants are unstable and their effectiveness is affected by several factors such as the number of microorganism present, the concentration of antimicrobial agent used and the storage temperature. One of the important factors that could enhance the effectiveness of antimicrobial activity in plants is the concentration of antimicrobial agent used. In this study, the plant extracts’ antifungal activity against A. flavus at various concentrations is evaluated via agar well diffusion method. Based on the results, 10 mg/ml of P. odorata has the lowest percentage of inhibition (35.7 %) meanwhile 90 mg/ml of both Z. mauritiana and P. odorata have the highest percentage of inhibition (85.7 %) against A. flavus.