Phytochemical composition and antioxidant properties on bark of Litsea garciae
The plants of the Litsea genus are widely explored concerning their nutritional and medicinal purposes. The recent study investigated the antioxidant capabilities and phytochemical composition of Litsea garciae (LG) bark’s hexane, chloroform, methanol, and aqueous extracts. Antioxidant measurements...
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Online Access: | http://ir.unimas.my/id/eprint/39311/2/Phytochemical%20composition.PDF http://ir.unimas.my/id/eprint/39311/ https://www.frontiersin.org/books/MSPP_34th_Scientific_Meeting_2021/4967 |
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my.unimas.ir.393112022-08-25T03:26:03Z http://ir.unimas.my/id/eprint/39311/ Phytochemical composition and antioxidant properties on bark of Litsea garciae SITI ZALEHA, RADUAN Muhammad Hamdi, Mahmood QAMAR UDDIN, AHMED ABDUL RAZAK, KASMURI WAN MOHD AZIZI, WAN SULAIMAN Muhammad Hamdi, Mahmood MUHAMAD RUSDI, AHMAD RUSMILI Md. Abdur, Rashid Mia MOHD FAROOQ, SHAIKH QK Botany RM Therapeutics. Pharmacology The plants of the Litsea genus are widely explored concerning their nutritional and medicinal purposes. The recent study investigated the antioxidant capabilities and phytochemical composition of Litsea garciae (LG) bark’s hexane, chloroform, methanol, and aqueous extracts. Antioxidant measurements were performed by determining the total phenolic content (TPC) and the total flavonoid content (TFC). Antioxidant capacities were assessed employing free radical scavenging (DPPH assay) and ferric reducing power (FRAP assay). The secondary metabolites composition was evaluated by Ultra-High-Performance Liquid Chromatography-Mass Spectrometry (UHPLC-MS) method. As a result, methanol extract was recorded to have the highest TPC value aligned with its positive appearance in phytochemical screening. Its antioxidant capacity indicated the least IC50. Results showed that the significant free radical scavenging activity was related to the presence of high phenolic content in the methanolic extract. UHPLC-MS analysis revealed significant variation in the secondary metabolites present in the methanol extract. The major phenolic compounds were found including N-trans-feruloyl-4-O-methyldopamine, N-cis-feruloyltyramine, epicatechin-(4beta->6)-epicatechin-(2beta->7,4beta->8)-epicatechin, 7-Hydroxy-3- (4-methoxyphenyl)-4-propyl-2H-1-benzopyran-2-one and 9-O-Methylneodunol. Overall, results have suggested LG bark to be a lead source for novel natural products possessing antioxidative potential. 2021 Proceeding PeerReviewed text en http://ir.unimas.my/id/eprint/39311/2/Phytochemical%20composition.PDF SITI ZALEHA, RADUAN and Muhammad Hamdi, Mahmood and QAMAR UDDIN, AHMED and ABDUL RAZAK, KASMURI and WAN MOHD AZIZI, WAN SULAIMAN and Muhammad Hamdi, Mahmood and MUHAMAD RUSDI, AHMAD RUSMILI and Md. Abdur, Rashid Mia and MOHD FAROOQ, SHAIKH (2021) Phytochemical composition and antioxidant properties on bark of Litsea garciae. In: MSPP 34th Scientific Meeting, 15-17 July 2021, Kuala Lumpur. https://www.frontiersin.org/books/MSPP_34th_Scientific_Meeting_2021/4967 |
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QK Botany RM Therapeutics. Pharmacology SITI ZALEHA, RADUAN Muhammad Hamdi, Mahmood QAMAR UDDIN, AHMED ABDUL RAZAK, KASMURI WAN MOHD AZIZI, WAN SULAIMAN Muhammad Hamdi, Mahmood MUHAMAD RUSDI, AHMAD RUSMILI Md. Abdur, Rashid Mia MOHD FAROOQ, SHAIKH Phytochemical composition and antioxidant properties on bark of Litsea garciae |
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The plants of the Litsea genus are widely explored concerning their nutritional and medicinal purposes. The recent study investigated the antioxidant capabilities
and phytochemical composition of Litsea garciae (LG) bark’s hexane, chloroform, methanol, and aqueous extracts. Antioxidant measurements were performed by determining the total phenolic content (TPC) and the total flavonoid
content (TFC). Antioxidant capacities were assessed employing free radical scavenging (DPPH assay) and ferric reducing power (FRAP assay). The secondary metabolites composition was evaluated by Ultra-High-Performance
Liquid Chromatography-Mass Spectrometry (UHPLC-MS) method. As a result, methanol extract was recorded to have the highest TPC value aligned with its positive appearance in phytochemical screening. Its antioxidant capacity indicated
the least IC50. Results showed that the significant free radical scavenging activity was related to the presence of high phenolic content in the methanolic extract. UHPLC-MS analysis revealed significant variation in the secondary
metabolites present in the methanol extract. The major phenolic compounds were found including N-trans-feruloyl-4-O-methyldopamine, N-cis-feruloyltyramine, epicatechin-(4beta->6)-epicatechin-(2beta->7,4beta->8)-epicatechin, 7-Hydroxy-3- (4-methoxyphenyl)-4-propyl-2H-1-benzopyran-2-one and 9-O-Methylneodunol. Overall, results have suggested LG bark to be a lead source for novel natural products possessing antioxidative potential. |
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SITI ZALEHA, RADUAN Muhammad Hamdi, Mahmood QAMAR UDDIN, AHMED ABDUL RAZAK, KASMURI WAN MOHD AZIZI, WAN SULAIMAN Muhammad Hamdi, Mahmood MUHAMAD RUSDI, AHMAD RUSMILI Md. Abdur, Rashid Mia MOHD FAROOQ, SHAIKH |
author_facet |
SITI ZALEHA, RADUAN Muhammad Hamdi, Mahmood QAMAR UDDIN, AHMED ABDUL RAZAK, KASMURI WAN MOHD AZIZI, WAN SULAIMAN Muhammad Hamdi, Mahmood MUHAMAD RUSDI, AHMAD RUSMILI Md. Abdur, Rashid Mia MOHD FAROOQ, SHAIKH |
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SITI ZALEHA, RADUAN |
title |
Phytochemical composition and antioxidant properties on bark of Litsea garciae |
title_short |
Phytochemical composition and antioxidant properties on bark of Litsea garciae |
title_full |
Phytochemical composition and antioxidant properties on bark of Litsea garciae |
title_fullStr |
Phytochemical composition and antioxidant properties on bark of Litsea garciae |
title_full_unstemmed |
Phytochemical composition and antioxidant properties on bark of Litsea garciae |
title_sort |
phytochemical composition and antioxidant properties on bark of litsea garciae |
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2021 |
url |
http://ir.unimas.my/id/eprint/39311/2/Phytochemical%20composition.PDF http://ir.unimas.my/id/eprint/39311/ https://www.frontiersin.org/books/MSPP_34th_Scientific_Meeting_2021/4967 |
_version_ |
1743110950293078016 |
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13.18916 |