SYNTHESIS, CHARACTERIZATION, IN SILICO OPTIMIZATION, AND CONFORMATIONAL STUDIES OF METHYL 4-O-PIVALOYL-αL-RHAMNOPYRANOSIDES

• Main Authors: Mohammed Mahbubul, Matin, Mohammad, Ibrahim, Tasnim Rahman, Anisa, Md. Rezaur, Rahman
• Format: Article
• Language: English
• Published: Faculty of Science, University of Malaya 2022
• Subjects: TP Chemical technology
• Online Access: http://ir.unimas.my/id/eprint/38541/1/SYNTHESIS%2C%20CHARACTERIZATION%20-%20Copy.pdf; http://ir.unimas.my/id/eprint/38541/; https://ejournal.um.edu.my/index.php/MJS/article/view/29058

Considering promising biological activities of natural and synthetic rhamnopyranoside esters, we have synthesized several methyl 4-O-pivaloyl-α-Lrhamnopyranosides via selective 2,3-O-acetonide protection of methyl α-Lrhamnopyranoside (4) followed by C-4 pivaloylation, and deprotection. The synthesiz...