Prophylactic topical tranexamic acid versus placebo in surgical patients: a systematic review and meta-analysis

• Main Authors: Wan Yi, Teoh, Tun Giap, Tan, Ka Ting, Ng, Ke Xin, Ong, Xue Lin, Chan, Samuel Ern Hung, Tsan, Chew Yin, Wang
• Format: Article
• Language: English
• Published: Wolters Kluwer Health, Inc. 2021
• Subjects: R Medicine (General); RD Surgery
• Online Access: http://ir.unimas.my/id/eprint/36632/1/prophylactic1.pdf; http://ir.unimas.my/id/eprint/36632/; https://journals.lww.com/annalsofsurgery/Abstract/2021/04000/Prophylactic_Topical_Tranexamic_Acid_Versus.10.aspx

Perioperative bleeding remains a major concern to all clinicians caring for perioperative patients. Due to the theoretical risk of thromboembolic events associated with tranexamic acid (TXA) when administered intravenously, topical route of TXA has been extensively studied, but its safety and eff...