Mutagenesis Analysis of ABCB8 Gene Promoter of Danio rerio

• Main Authors: Chung, Hung Hui, LAI, PEI NI, LEONARD, WHYE KIT LIM
• Format: Article
• Language: English
• Published: UNIMAS Publisher 2021
• Subjects: QL Zoology; SH Aquaculture. Fisheries. Angling
• Online Access: http://ir.unimas.my/id/eprint/35533/3/mutagenesis-converted.pdf; http://ir.unimas.my/id/eprint/35533/; https://publisher.unimas.my/ojs/index.php/TUR/issue/view/178/83; https://doi.org/10.33736/tur.2500.2021

The ABCB8 is one of the members under the ABCB subfamily of ATP-Binding Cassette (ABC) transporter which possess the ability in regulating the intracellular iron and heme transport. The loss of function mutation of ABCB8 gene leads to iron and heme accumulation in the cell which is highly toxic to h...