First detection of a novel ‘unknown host’ flavivirus in a Malaysian rodent
Current phylogenetic analysis of the flavivirus genus has identified a group of mosquito-borne viruses for which the vertebrate hosts are currently unknown. Here we report the identification of a novel member of this group from a peridomestic rodent species (Sundamys muelleri) collected in Sarawak,...
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Microbiology Society
2021
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Online Access: | http://ir.unimas.my/id/eprint/35396/1/First%20detection%20of%20a%20novel%20%E2%80%98unknown%20host%E2%80%99%20flavivirus%20in%20a%20Malaysian%20rodent.pdf http://ir.unimas.my/id/eprint/35396/ https://www.microbiologyresearch.org/content/journal/acmi/10.1099/acmi.0.000223?crawler=true https://doi.org/10.1099/acmi.0.000223 |
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my.unimas.ir.353962021-05-31T08:21:19Z http://ir.unimas.my/id/eprint/35396/ First detection of a novel ‘unknown host’ flavivirus in a Malaysian rodent Blasdell, Kim R. Wynne, James W. Perera, David Firth, Cadhla Q Science (General) QL Zoology QR355 Virology Current phylogenetic analysis of the flavivirus genus has identified a group of mosquito-borne viruses for which the vertebrate hosts are currently unknown. Here we report the identification of a novel member of this group from a peridomestic rodent species (Sundamys muelleri) collected in Sarawak, Malaysia in 2016. We propose to name this novel flavivirus Batu Kawa virus after the location in which it was identified, with the abbreviation BKWV. Characterization of the BKWV genome allowed identification of putative mature peptides, potential enzyme motifs and conserved structural elements. Phylogenetic analysis found BKWV to be most closely related to Nhumirim virus (from Brazil) and Barkedji virus (from Senegal and Israel). Both of these viruses have been identified in Culex mosquitoes and belong to a group of viruses with unknown vertebrate hosts. This is the first known report of a member of this group of viruses from a potential mammalian host. Microbiology Society 2021-04-15 Article PeerReviewed text en http://ir.unimas.my/id/eprint/35396/1/First%20detection%20of%20a%20novel%20%E2%80%98unknown%20host%E2%80%99%20flavivirus%20in%20a%20Malaysian%20rodent.pdf Blasdell, Kim R. and Wynne, James W. and Perera, David and Firth, Cadhla (2021) First detection of a novel ‘unknown host’ flavivirus in a Malaysian rodent. Access Microbiology, 3 (4). pp. 1-8. https://www.microbiologyresearch.org/content/journal/acmi/10.1099/acmi.0.000223?crawler=true https://doi.org/10.1099/acmi.0.000223 |
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Q Science (General) QL Zoology QR355 Virology Blasdell, Kim R. Wynne, James W. Perera, David Firth, Cadhla First detection of a novel ‘unknown host’ flavivirus in a Malaysian rodent |
description |
Current phylogenetic analysis of the flavivirus genus has identified a group of mosquito-borne viruses for which the vertebrate hosts are currently unknown. Here we report the identification of a novel member of this group from a peridomestic rodent species (Sundamys muelleri) collected in Sarawak, Malaysia in 2016. We propose to name this novel flavivirus Batu Kawa virus after the location in which it was identified, with the abbreviation BKWV. Characterization of the BKWV genome allowed identification of putative mature peptides, potential enzyme motifs and conserved structural elements. Phylogenetic analysis found BKWV to be most closely related to Nhumirim virus (from Brazil) and Barkedji virus (from Senegal and Israel). Both of these viruses have been identified in Culex mosquitoes and belong to a group of viruses with unknown vertebrate hosts. This is the first known report of a member of this group of viruses from a potential mammalian host. |
format |
Article |
author |
Blasdell, Kim R. Wynne, James W. Perera, David Firth, Cadhla |
author_facet |
Blasdell, Kim R. Wynne, James W. Perera, David Firth, Cadhla |
author_sort |
Blasdell, Kim R. |
title |
First detection of a novel ‘unknown host’ flavivirus in a Malaysian rodent |
title_short |
First detection of a novel ‘unknown host’ flavivirus in a Malaysian rodent |
title_full |
First detection of a novel ‘unknown host’ flavivirus in a Malaysian rodent |
title_fullStr |
First detection of a novel ‘unknown host’ flavivirus in a Malaysian rodent |
title_full_unstemmed |
First detection of a novel ‘unknown host’ flavivirus in a Malaysian rodent |
title_sort |
first detection of a novel ‘unknown host’ flavivirus in a malaysian rodent |
publisher |
Microbiology Society |
publishDate |
2021 |
url |
http://ir.unimas.my/id/eprint/35396/1/First%20detection%20of%20a%20novel%20%E2%80%98unknown%20host%E2%80%99%20flavivirus%20in%20a%20Malaysian%20rodent.pdf http://ir.unimas.my/id/eprint/35396/ https://www.microbiologyresearch.org/content/journal/acmi/10.1099/acmi.0.000223?crawler=true https://doi.org/10.1099/acmi.0.000223 |
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1702173272715558912 |
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13.160551 |