Zebrafish (Danio rerio) ecotoxicological ABCB4, ABCC1 and ABCG2a gene promoters depict spatiotemporal xenobiotic multidrug resistance properties against environmental pollutants

• Main Authors: Chung, Hung Hui, Whye, Leonard Kit Lim, Sairatul Dahlianis, Ishak, Waiho, Khor
• Format: Article
• Language: English
• Published: Elsevier Inc. 2021
• Subjects: Q Science (General); QL Zoology; SH Aquaculture. Fisheries. Angling
• Online Access: http://ir.unimas.my/id/eprint/34985/1/Chung%20Hung%20Hui.pdf; http://ir.unimas.my/id/eprint/34985/; https://www.sciencedirect.com/science/article/pii/S2452014421000959?dgcid=coauthor; https://doi.org/10.1016/j.genrep.2021.101110

Marine organisms are naturally equipped with multixenobiotic resistance mechanisms that are often governed by ATP-binding cassette (ABC) transporter family members. Previous studies focused on the target genes of ABC but little is known about the functionality of their promoter regions. Due to the i...