Mutagenesis Analysis of ABCB4 Gene Promoter of Danio rerio

• Main Authors: Yeaw, Zi Xuan, Whye, Leonard Kit Lim, Chung, Hung Hui
• Format: Article
• Language: English
• Published: UNIMAS Publisher 2020
• Subjects: Q Science (General); QL Zoology
• Online Access: http://ir.unimas.my/id/eprint/33616/1/Mutagenesis%20Analysis%20of%20ABCB4%20Gene%20Promoter%20of%20Danio%20rerio.pdf; http://ir.unimas.my/id/eprint/33616/; http://publisher.unimas.my/ojs/index.php/TUR/article/view/2499

Zebrafish abcb4 gene (ortholog to human ABCB1 gene) serves primarily in multidrug resistance (MDR)mechanism by effluxing chemotherapeutic agents, chemicals, xenobiotics, and numerous anti-cancer drugs out of the cells. This study aims to identify the specific transcription factor binding sites (TFBS...