Human coronaviruses : ophthalmic manifestations
The 2019 novel coronavirus which causes severe acute respiratory syndrome (SARS) known as SARS-CoV-2 still remains as a global pandemic since its discovery and continues to spread across the world, given how highly contagious the virus is. We reviewed various articles that explore eye involvement in...
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Online Access: | http://ir.unimas.my/id/eprint/32562/1/Human%20coronaviruses%20ophthalmic%20%20manifestations_pdf.pdf http://ir.unimas.my/id/eprint/32562/ https://bmjophth.bmj.com/content/5/1/e000630.full?ijkey=BpxH8k5CT7PgBYo&keytype=ref |
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my.unimas.ir.325622023-05-19T02:30:10Z http://ir.unimas.my/id/eprint/32562/ Human coronaviruses : ophthalmic manifestations Abdul Kadir, Mohd Asyraaf Lim, Lik Thai R Medicine (General) The 2019 novel coronavirus which causes severe acute respiratory syndrome (SARS) known as SARS-CoV-2 still remains as a global pandemic since its discovery and continues to spread across the world, given how highly contagious the virus is. We reviewed various articles that explore eye involvement in COVID-19 and other human coronaviruses, its human manifestations in comparison to animal studies and potential mechanism of viral entry into the eye surface. Evidence of animal studies depicted various complications of coronaviruses infection into the eyes, in both anterior and posterior segments of the eye. Conjunctival inflammation remains uncommon in association with COVID-19, with other ophthalmic findings. The risk of transmission via the ocular surface remains likely low, though it is inarguably present based on preliminary finding of viral load in ocular samples and expression of ACE2 on the ocular surface. Testing the tears sample for diagnosing SARS-CoV-2 was unreliable due to limitations of the testing kits and conflicting evidence of the viral titre in the ocular samples. Further larger, more precise and specific studies are required to allow us to better understand the pattern of virulence underlying the associations of SARS-CoV-2 in the eye despite its rare occurrence. This review article aims to enhance better awareness among clinicians regarding ocular manifestations associated with COVID-19 and necessary precautions should be implemented to minimise the risk of person-to-person especially in the nosocomial setting. BMJ Publishing Group Ltd 2020 Article PeerReviewed text en http://ir.unimas.my/id/eprint/32562/1/Human%20coronaviruses%20ophthalmic%20%20manifestations_pdf.pdf Abdul Kadir, Mohd Asyraaf and Lim, Lik Thai (2020) Human coronaviruses : ophthalmic manifestations. BMJ Open Ophthalmology, 5 (1). pp. 1-8. ISSN 2397-3269 https://bmjophth.bmj.com/content/5/1/e000630.full?ijkey=BpxH8k5CT7PgBYo&keytype=ref doi:10.1136/bmjophth-2020-000630 |
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R Medicine (General) Abdul Kadir, Mohd Asyraaf Lim, Lik Thai Human coronaviruses : ophthalmic manifestations |
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The 2019 novel coronavirus which causes severe acute respiratory syndrome (SARS) known as SARS-CoV-2 still remains as a global pandemic since its discovery and continues to spread across the world, given how highly contagious the virus is. We reviewed various articles that explore eye involvement in COVID-19 and other human coronaviruses, its human manifestations in comparison to animal studies and potential mechanism of viral entry into the eye surface. Evidence of animal studies depicted various complications of coronaviruses infection into the eyes, in both anterior and posterior segments of the eye. Conjunctival inflammation remains uncommon in association with COVID-19, with other ophthalmic findings. The risk of transmission via the ocular surface remains likely low, though it is inarguably present based on preliminary finding of viral load in ocular samples and expression of ACE2 on the ocular surface. Testing the tears sample for diagnosing SARS-CoV-2 was unreliable due to limitations of the testing kits and conflicting evidence of the viral titre in the ocular samples. Further larger, more precise and specific studies are required to allow us to better understand the pattern of virulence underlying the associations of SARS-CoV-2 in the eye despite its rare occurrence. This review article aims to enhance better awareness among clinicians regarding ocular manifestations associated with COVID-19 and necessary precautions should be implemented to minimise the risk of person-to-person especially in the nosocomial setting. |
format |
Article |
author |
Abdul Kadir, Mohd Asyraaf Lim, Lik Thai |
author_facet |
Abdul Kadir, Mohd Asyraaf Lim, Lik Thai |
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Abdul Kadir, Mohd Asyraaf |
title |
Human coronaviruses : ophthalmic manifestations |
title_short |
Human coronaviruses : ophthalmic manifestations |
title_full |
Human coronaviruses : ophthalmic manifestations |
title_fullStr |
Human coronaviruses : ophthalmic manifestations |
title_full_unstemmed |
Human coronaviruses : ophthalmic manifestations |
title_sort |
human coronaviruses : ophthalmic manifestations |
publisher |
BMJ Publishing Group Ltd |
publishDate |
2020 |
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http://ir.unimas.my/id/eprint/32562/1/Human%20coronaviruses%20ophthalmic%20%20manifestations_pdf.pdf http://ir.unimas.my/id/eprint/32562/ https://bmjophth.bmj.com/content/5/1/e000630.full?ijkey=BpxH8k5CT7PgBYo&keytype=ref |
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