Naturally Acquired Human Plasmodium cynomolgi and P. knowlesi Infections, Malaysian Borneo
To monitor the incidence of Plasmodium knowlesi infections and determine whether other simian malaria parasites are being transmitted to humans, we examined 1,047 blood samples from patients with malaria at Kapit Hospital in Kapit, Malaysia, during June 24, 2013–December 31, 2017. Using nested PCR a...
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2020
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Online Access: | http://ir.unimas.my/id/eprint/30775/1/Naturally.pdf http://ir.unimas.my/id/eprint/30775/ https://wwwnc.cdc.gov/eid/article/26/8/20-0343_article |
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my.unimas.ir.307752021-05-24T07:07:26Z http://ir.unimas.my/id/eprint/30775/ Naturally Acquired Human Plasmodium cynomolgi and P. knowlesi Infections, Malaysian Borneo Raja, Thamayanthi Nada Hu, Ting Huey Khamisah, Abdul Kadir Dayang Shuaishah, Awang Mohamad Rosli, Nawal Wong, Lolita Lin Hii, King Ching Divis, Paul Cliff Simon Singh, Balbir Q Science (General) QR Microbiology RA0421 Public health. Hygiene. Preventive Medicine To monitor the incidence of Plasmodium knowlesi infections and determine whether other simian malaria parasites are being transmitted to humans, we examined 1,047 blood samples from patients with malaria at Kapit Hospital in Kapit, Malaysia, during June 24, 2013–December 31, 2017. Using nested PCR assays, we found 845 (80.6%) patients had either P. knowlesi monoinfection (n = 815) or co-infection with other Plasmodium species (n = 30). We noted the annual number of these zoonotic infections increased greatly in 2017 (n = 284). We identified 6 patients, 17–65 years of age, with P. cynomolgi and P. knowlesi co-infections, confirmed by phylogenetic analyses of the Plasmodium cytochrome c oxidase subunit 1 gene sequences. P. knowlesi continues to be a public health concern in the Kapit Division of Sarawak, Malaysian Borneo. In addition, another simian malaria parasite, P. cynomolgi, also is an emerging cause of malaria in humans. CDC Centers of Disease Control and Prevention 2020-07-14 Article PeerReviewed text en http://ir.unimas.my/id/eprint/30775/1/Naturally.pdf Raja, Thamayanthi Nada and Hu, Ting Huey and Khamisah, Abdul Kadir and Dayang Shuaishah, Awang Mohamad and Rosli, Nawal and Wong, Lolita Lin and Hii, King Ching and Divis, Paul Cliff Simon and Singh, Balbir (2020) Naturally Acquired Human Plasmodium cynomolgi and P. knowlesi Infections, Malaysian Borneo. Emerging Infectious Diseases, 26 (8). pp. 1801-1809. ISSN 1080-6059 https://wwwnc.cdc.gov/eid/article/26/8/20-0343_article DOI:10.3201/eid2608.200343 |
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Q Science (General) QR Microbiology RA0421 Public health. Hygiene. Preventive Medicine Raja, Thamayanthi Nada Hu, Ting Huey Khamisah, Abdul Kadir Dayang Shuaishah, Awang Mohamad Rosli, Nawal Wong, Lolita Lin Hii, King Ching Divis, Paul Cliff Simon Singh, Balbir Naturally Acquired Human Plasmodium cynomolgi and P. knowlesi Infections, Malaysian Borneo |
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To monitor the incidence of Plasmodium knowlesi infections and determine whether other simian malaria parasites are being transmitted to humans, we examined 1,047 blood samples from patients with malaria at Kapit Hospital in Kapit, Malaysia, during June 24, 2013–December 31, 2017. Using nested PCR assays, we found 845 (80.6%) patients had either P. knowlesi monoinfection (n = 815) or co-infection with other Plasmodium species (n = 30). We noted the annual number of these zoonotic infections increased greatly in 2017 (n = 284). We identified 6 patients, 17–65 years of age, with P. cynomolgi and P. knowlesi co-infections, confirmed by phylogenetic analyses of the Plasmodium cytochrome c oxidase subunit 1 gene sequences. P. knowlesi continues to be a public health concern in the Kapit Division of Sarawak, Malaysian Borneo. In addition, another simian malaria parasite, P. cynomolgi, also is an emerging cause of malaria in humans. |
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Article |
author |
Raja, Thamayanthi Nada Hu, Ting Huey Khamisah, Abdul Kadir Dayang Shuaishah, Awang Mohamad Rosli, Nawal Wong, Lolita Lin Hii, King Ching Divis, Paul Cliff Simon Singh, Balbir |
author_facet |
Raja, Thamayanthi Nada Hu, Ting Huey Khamisah, Abdul Kadir Dayang Shuaishah, Awang Mohamad Rosli, Nawal Wong, Lolita Lin Hii, King Ching Divis, Paul Cliff Simon Singh, Balbir |
author_sort |
Raja, Thamayanthi Nada |
title |
Naturally Acquired Human Plasmodium cynomolgi and P. knowlesi Infections, Malaysian Borneo |
title_short |
Naturally Acquired Human Plasmodium cynomolgi and P. knowlesi Infections, Malaysian Borneo |
title_full |
Naturally Acquired Human Plasmodium cynomolgi and P. knowlesi Infections, Malaysian Borneo |
title_fullStr |
Naturally Acquired Human Plasmodium cynomolgi and P. knowlesi Infections, Malaysian Borneo |
title_full_unstemmed |
Naturally Acquired Human Plasmodium cynomolgi and P. knowlesi Infections, Malaysian Borneo |
title_sort |
naturally acquired human plasmodium cynomolgi and p. knowlesi infections, malaysian borneo |
publisher |
CDC Centers of Disease Control and Prevention |
publishDate |
2020 |
url |
http://ir.unimas.my/id/eprint/30775/1/Naturally.pdf http://ir.unimas.my/id/eprint/30775/ https://wwwnc.cdc.gov/eid/article/26/8/20-0343_article |
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1701166532658200576 |
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