In vitro cytotoxicity evaluation of thioureaderivatives bearing Salix sp. constituent againstHK-1 cell lines

• Main Authors: Norsyafikah Asyilla, Nordin, Vannessa, Lawai, Zainab, Ngaini, Ainaa Nadiah, Abd Halim, Siaw, San Hwang, Reagan, Entigu Linton, Boon, Kiat Lee, Paul Matthew, Neilsen
• Format: E-Article
• Language: English
• Published: Taylor & Francis Group 2020
• Subjects: Q Science (General)
• Online Access: http://ir.unimas.my/id/eprint/30123/1/In%20vitro%20cytotoxicity%20evaluation%20of%20thioureaderivatives%20bearing%20Salix%20sp.%20constituent%20againstHK-1%20cell%20lines_Abstract.pdf; http://ir.unimas.my/id/eprint/30123/; https://www.tandfonline.com/loi/gnpl20

In searching for drugs from natural product scaffolds has gained inter-est among researchers. In this study, a series of twelve halogenatedthiourea (ATX 1-12)viachemical modification of aspirin (a naturalproduct derivative) and evaluated for cytotoxic activity against naso-pharyngeal carcinoma (NPC)...