Low prevalence of the BCR–ABL1 fusion gene in a normal population in southern Sarawak

• Main Authors: Anselm, Su Ting, Lim, Isabel Fong, Lela, Binti Suut, Jew, Win Kuan, Siow, Phing Tay, Kubota, Sho, Osato, Motomi, Sashida, Goro
• Format: Article
• Language: English
• Published: Springer Nature Switzerland 2019
• Subjects: QR Microbiology; RA0421 Public health. Hygiene. Preventive Medicine
• Online Access: http://ir.unimas.my/id/eprint/28473/1/Anselm%20Su%20Ting.pdf; http://ir.unimas.my/id/eprint/28473/; https://link.springer.com/article/10.1007/s12185-019-02768-x

The BCR–ABL1 fusion gene is the driver mutation of Philadelphia chromosome-positive chronic myeloid leukemia (CML). Its expression level in CML patients is monitored by a real-time quantitative polymerase chain reaction defned by the International Scale (qPCRIS). BCR–ABL1 has also been found in asym...