Synthesis of asprin thiourea derivative and its antibacterial studies
A new series ofAspirin - thiourea derivatives have been synthesized for biological interest by addition of active amine groups like Para-ansidine, Orto-anisidine, Ortotoluidin and Para-Chloroaniline. The structure of synthesized compound was characterized by IR, IHNMR and IlCNMR. The synthesized com...
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| Main Author: | |
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| Format: | Final Year Project Report |
| Language: | English |
| Published: |
Universiti Malaysia Sarawak (UNIMAS)
2014
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| Online Access: | http://ir.unimas.my/id/eprint/26275/1/Abyrami%20AP%20Muniandy%20ft.pdf http://ir.unimas.my/id/eprint/26275/ |
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| Summary: | A new series ofAspirin - thiourea derivatives have been synthesized for biological interest by addition of active amine groups like Para-ansidine, Orto-anisidine, Ortotoluidin and Para-Chloroaniline. The structure of synthesized compound was characterized by IR, IHNMR and IlCNMR. The synthesized compounds were screened for their antibacterial activity using Gram negative bacteria (Ecoli) using Disc diffusion method.2- {[(2methylphenyl)carbamothioyl] carbamoyl) phenyl acetate
showed excellent inhibition against Ecoli compared to all synthesized compound. |
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