Synthesis and Characterisation of Bis(thiourea) Derivatives and Studies of their Biological Properties

• Main Author: Ainaa Nadiah, Abd Halim
• Format: Thesis
• Language: English
• Published: Universiti Malaysia Sarawak, (UNIMAS) 2017
• Subjects: Q Science (General); QD Chemistry; QK Botany
• Online Access: http://ir.unimas.my/id/eprint/23866/5/Ainaa%20Nadiah.pdf; http://ir.unimas.my/id/eprint/23866/

Five series of novel bis(thiourea) derivatives 41a-e, 42a-l, 43a-f, 46a-c and 50a-f bearing different pharmacophores have been successfully synthesised via nucleophilic substitution reaction of benzene-1,4-dicarbonyl isothiocyanate intermediate 52 with various amines derivatives. Preparations of...