Association between Clinical Parameters and CRT Response
Background: CRT is indicated for patients with severely impaired left ventricular systolic function and ventricular dyssynchrony who remain symptomatic despite optimal medical therapy. CRT is an expensive treatment with a significant non-responder rate. Objective: To ensure appropriate use of this...
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Main Authors: | , , , , , , , , , , , |
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格式: | E-Article |
語言: | English |
出版: |
Elsevier
2018
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在線閱讀: | http://ir.unimas.my/id/eprint/22937/1/Association%20between%20Clinical%20Parameters%20and%20CRT%20Response.pdf http://ir.unimas.my/id/eprint/22937/ https://www.journals.elsevier.com/international-journal-of-cardiology |
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總結: | Background: CRT is indicated for patients with severely impaired left ventricular systolic function and ventricular dyssynchrony who remain symptomatic despite optimal medical therapy. CRT is an expensive treatment with a significant non-responder rate.
Objective: To ensure appropriate use of this treatment modality, we decided to investigate whether clinical parameters can predict response to CRT in our patients.
Methods: We retrospectively reviewed all CRT patients under responder based on pre-specified ECHO and clinical criteria. An ECHO response would be: relative improvement from baseline left ventricular ejection fraction (EF) of N 15%; and a decrease in End Diastolic Volume index (EDVi) or End Systolic Volume index (ESVi) of N 15%. Clinical response was defined as an improvement of at least 1 NYHA functional class. Patients who fulfil both ECHO and clinical criteria are considered responders
our follow-up since 2014. We classified them as responder or non. |
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