Bacterial antimutagenesis by hydroxycinnamic acids from plant cell walls

• Main Authors: Ferguson, L.R, Lim, I.F, Pearson, A.E, Ralph, J., Harris, P.J.
• Format: Article
• Language: English
• Published: Mutation Research/Genetic Toxicology and Environmental Mutagenesis 2003
• Subjects: R Medicine (General); RV Botanic, Thomsonian, and eclectic medicine
• Online Access: http://ir.unimas.my/id/eprint/2216/1/Mutation.pdf; http://ir.unimas.my/id/eprint/2216/; http://www.sciencedirect.com/science/article/pii/S1383571803002316

We have determined the abilities of (E)-ferulic acid, (E)-p-coumaric acid and (E,E)-5-5-dehydrodiferulic acid to protect against different types of mutation in a simple bacterial model. These antimutagenic properties were compared with those of the related compound curcumin, and also with those of a...