Antimicrobial Activity of Kaempferia Galanga Rhizome against Biofilm of Vibrio Cholerae Outbreak from Limbang Sarawak
Kaempferia galangal rhizome is one of the traditional medicinal plant species in Zingiberaceae family and well known as “cekur” in Borneo. Rapid emergence of multidrug resistance of V. cholerae biofilm has increased the failure of antibiotic treatment in recent years. This research was designed t...
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my.unimas.ir.214722018-09-07T01:53:12Z http://ir.unimas.my/id/eprint/21472/ Antimicrobial Activity of Kaempferia Galanga Rhizome against Biofilm of Vibrio Cholerae Outbreak from Limbang Sarawak Elexson, N.A. QR Microbiology Kaempferia galangal rhizome is one of the traditional medicinal plant species in Zingiberaceae family and well known as “cekur” in Borneo. Rapid emergence of multidrug resistance of V. cholerae biofilm has increased the failure of antibiotic treatment in recent years. This research was designed to demonstrate the antimicrobial activity of K. galangal rhizome extract against twenty six (n=26) V. cholera biofilm which were isolated from outbreak in Limbang, Sarawak in 2016. K. galangal rhizome was analyzed by methanol extraction and tested against biofilm of V. cholerae. The susceptibility of V. cholerae towards K. galangal rhizome was evaluated using disk diffusion method which showed a maximum zone of inhibition of 12.0 mm at 1000 mg/mL concentration. As a result, the MBEC50 of V. cholerae was between 125 mg/mL to 250 mg/mL while more than 90% biofilm eradication (MBEC90) was achieved by 500 mg/mL extract concentration. Extract-treated cell showed change in the morphology of V. cholerae by destruction of cell wall. K. galangal rhizome extract acts as a potent antibiofilm agent with dual actions by preventing and eradicating the biofilm of V. cholerae. Akademia baru 2018-07-07 E-Article PeerReviewed text en http://ir.unimas.my/id/eprint/21472/8/ARASETV12_N1_P24_31%20%28abstract%29.pdf Elexson, N.A. (2018) Antimicrobial Activity of Kaempferia Galanga Rhizome against Biofilm of Vibrio Cholerae Outbreak from Limbang Sarawak. Journal of Advanced Research in Applied Sciences and Engineering Technology, 12 (1). pp. 24-31. ISSN 2462-1943 http://www.akademiabaru.com/doc/ARASETV12_N1_P24_31.pdf Volume 12, Issue 1 (2018) 24-31 |
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QR Microbiology Elexson, N.A. Antimicrobial Activity of Kaempferia Galanga Rhizome against Biofilm of Vibrio Cholerae Outbreak from Limbang Sarawak |
description |
Kaempferia galangal rhizome is one of the traditional medicinal plant species in
Zingiberaceae family and well known as “cekur” in Borneo. Rapid emergence of
multidrug resistance of V. cholerae biofilm has increased the failure of antibiotic
treatment in recent years. This research was designed to demonstrate the
antimicrobial activity of K. galangal rhizome extract against twenty six (n=26) V. cholera
biofilm which were isolated from outbreak in Limbang, Sarawak in 2016. K. galangal
rhizome was analyzed by methanol extraction and tested against biofilm of V. cholerae.
The susceptibility of V. cholerae towards K. galangal rhizome was evaluated using disk
diffusion method which showed a maximum zone of inhibition of 12.0 mm at 1000
mg/mL concentration. As a result, the MBEC50 of V. cholerae was between 125 mg/mL
to 250 mg/mL while more than 90% biofilm eradication (MBEC90) was achieved by 500
mg/mL extract concentration. Extract-treated cell showed change in the morphology
of V. cholerae by destruction of cell wall. K. galangal rhizome extract acts as a potent
antibiofilm agent with dual actions by preventing and eradicating the biofilm of V.
cholerae. |
format |
E-Article |
author |
Elexson, N.A. |
author_facet |
Elexson, N.A. |
author_sort |
Elexson, N.A. |
title |
Antimicrobial Activity of Kaempferia Galanga Rhizome against Biofilm of Vibrio Cholerae Outbreak from Limbang Sarawak |
title_short |
Antimicrobial Activity of Kaempferia Galanga Rhizome against Biofilm of Vibrio Cholerae Outbreak from Limbang Sarawak |
title_full |
Antimicrobial Activity of Kaempferia Galanga Rhizome against Biofilm of Vibrio Cholerae Outbreak from Limbang Sarawak |
title_fullStr |
Antimicrobial Activity of Kaempferia Galanga Rhizome against Biofilm of Vibrio Cholerae Outbreak from Limbang Sarawak |
title_full_unstemmed |
Antimicrobial Activity of Kaempferia Galanga Rhizome against Biofilm of Vibrio Cholerae Outbreak from Limbang Sarawak |
title_sort |
antimicrobial activity of kaempferia galanga rhizome against biofilm of vibrio cholerae outbreak from limbang sarawak |
publisher |
Akademia baru |
publishDate |
2018 |
url |
http://ir.unimas.my/id/eprint/21472/8/ARASETV12_N1_P24_31%20%28abstract%29.pdf http://ir.unimas.my/id/eprint/21472/ http://www.akademiabaru.com/doc/ARASETV12_N1_P24_31.pdf |
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1644513531547090944 |
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13.159267 |