Double Carbonylation Using Glyoxal (HCOCOH): A Practical Copper-Promoted Synthesis of Isatins from Primary and Secondary Anilines

A novel double carbonylation process has been demonstrated with easily available HCOCOH (glyoxal) as the double carbonylation reagent. Simple CuCl2·2H2O (copper(II) chloride dihydrate) was used as the oxidant for this transformation. Under optimized reaction conditions, various primary and secondary...

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Bibliographic Details
Main Authors: Hui, Suzie Chin Kuan, Wei, Sun, Lu, Wang, Chungu, Xia, Meng, Guan Tay, Chao, Liu
Format: E-Article
Published: WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim 2017
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Online Access:http://ir.unimas.my/id/eprint/17313/
http://onlinelibrary.wiley.com/doi/10.1002/adsc.201700583/full
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