Extreme geographical fixation of variation in the Plasmodium falciparum gamete surface protein gene Pfs48 /45 compared with microsatellite loci

• Main Authors: Conway, D.J., Machado, Ricardo L.D., Balbir, Singh, Dessert, Patricia, Mikes, Zsuzsanna S., Povoa, Marinete M., Oduola, Ayoade M.J., Roper, Cally
• Format: E-Article
• Language: English
• Published: Elsevier Science B.V. 2001
• Subjects: Q Science (General)
• Online Access: http://ir.unimas.my/id/eprint/15849/1/Extreme%20geographical%20fixation%20of%20variation%20in%20the%20Plasmodium%20falciparum%20gamete%20%28abstract%29.pdf; http://ir.unimas.my/id/eprint/15849/; http://www.sciencedirect.com/science/article/pii/S016668510100278X

Comparing patterns of genetic variation at multiple loci in the genome of a species can potentially identify loci which are under selection. The large number of polymorphic microsatellites in the malaria parasite Plasmodium falciparum are available markers to screen for selectively important loci....