Cytoadherence and virulence - the case of Plasmodium knowlesi malaria

• Main Authors: Farrah, A Fatih, Siner, Angela, Atique M, Ahmed, Lu, Chan Woon, Craig, Alister G, Balbir, Singh, Sanjeev, Krishna, Cox-Singh, J.
• Format: Article
• Language: English
• Published: BioMed Central Ltd. 2012
• Subjects: RV Botanic, Thomsonian, and eclectic medicine
• Online Access: http://ir.unimas.my/id/eprint/15793/1/Cytoadherence.pdf; http://ir.unimas.my/id/eprint/15793/; https://malariajournal.biomedcentral.com/articles/10.1186/1475-2875-11-33

Background: Cytoadherence of infected red blood cells to brain endothelium is causally implicated in malarial coma, one of the severe manifestations of falciparum malaria. Cytoadherence is mediated by specific binding of variant parasite antigens, expressed on the surface of infected erythrocytes,...